Enantioselective Carbonyl Catalysis Enabled by Chiral Aldehydes.
Mannich reaction
asymmetric catalysis
carbonyl catalysis
chiral aldehydes
organocatalysis
Journal
Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543
Informations de publication
Date de publication:
20 05 2019
20 05 2019
Historique:
received:
29
07
2018
pubmed:
15
9
2018
medline:
15
9
2018
entrez:
15
9
2018
Statut:
ppublish
Résumé
Organocatalytic methods have achieved spectacular advancements for the preparation of chiral molecules in highly enantioenriched forms. The fast development of this field can mainly be attributed to the evolution of general and reliable activation modes. The discovery and identification of new activation modes are therefore highly desirable to push the boundaries of asymmetric reactions. In this Minireview, recent advances in enantioselective carbonyl catalysis, one useful subbranch of organocatalysis for the efficient activation of simple amines, will be summarized. With elegantly designed chiral aldehyde catalysts, highly enantioselective and efficient asymmetric reactions can be developed. Continued development of enantioselective carbonyl catalysis is expected in the future.
Identifiants
pubmed: 30216640
doi: 10.1002/anie.201808700
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6818-6825Subventions
Organisme : National Natural Science Foundation of China
ID : 21332009
Pays : International
Informations de copyright
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.