Diaphragm muscle function following midcervical contusion injury in rats.
Pdi
breathing
contusion
diaphragm
spinal cord injury
Journal
Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Titre abrégé: J Appl Physiol (1985)
Pays: United States
ID NLM: 8502536
Informations de publication
Date de publication:
01 01 2019
01 01 2019
Historique:
pubmed:
22
9
2018
medline:
10
3
2020
entrez:
22
9
2018
Statut:
ppublish
Résumé
Midcervical spinal cord contusion injury results in tissue damage, disruption of spinal pathways, and motor neuron loss. Unilateral C4 contusion results in loss of 40%-50% of phrenic motor neurons ipsilateral to the injury (~25% of the total phrenic motor neuron pool). Over time after unilateral C4 contusion injury, diaphragm muscle (DIAm) electromyogram activity increases both contralateral and ipsilateral to the side of injury in rats, suggesting compensation because of increased activation of the surviving motor neurons. However, the impact of contusion injury on DIAm force generation is less clear. Transdiaphragmatic pressure (Pdi) was measured across motor behaviors over time after unilateral C4 contusion injury in adult male Sprague-Dawley rats. Maximum Pdi (Pdi
Identifiants
pubmed: 30236045
doi: 10.1152/japplphysiol.00481.2018
pmc: PMC6383644
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
221-230Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL096750
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL146114
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL105355
Pays : United States
Références
Respir Physiol Neurobiol. 2010 Aug 31;173(1):101-6
pubmed: 20620243
Am Rev Respir Dis. 1988 Oct;138(4):862-6
pubmed: 3202460
Pulm Pharmacol Ther. 2015 Dec;35:105-10
pubmed: 26549786
J Appl Physiol (1985). 1985 May;58(5):1469-76
pubmed: 3158636
J Appl Physiol (1985). 1998 Sep;85(3):1123-34
pubmed: 9729591
Exp Gerontol. 2013 Sep;48(9):881-7
pubmed: 23792145
Muscle Nerve. 1998 Jul;21(7):887-95
pubmed: 9626248
Exp Neurol. 2008 May;211(1):97-106
pubmed: 18308305
Exp Neurol. 2011 Sep;231(1):97-103
pubmed: 21683697
Brain Res. 1986 Aug 20;380(2):287-96
pubmed: 3756481
Exp Neurol. 1987 May;96(2):443-55
pubmed: 3569466
J Appl Physiol (1985). 1989 Jan;66(1):350-9
pubmed: 2917941
J Appl Physiol (1985). 2003 Apr;94(4):1467-72
pubmed: 12626472
Respir Physiol Neurobiol. 2015 Aug 15;215:73-81
pubmed: 26003850
Prog Brain Res. 2014;209:309-29
pubmed: 24746055
J Appl Physiol (1985). 1990 Jun;68(6):2296-304
pubmed: 2384409
Respir Physiol. 1976 Feb;26(1):113-28
pubmed: 179122
J Physiol. 1992 Nov;457:167-76
pubmed: 1297831
J Appl Physiol (1985). 2007 Jun;102(6):2332-7
pubmed: 17317870
Respir Physiol Neurobiol. 2005 Jul 28;147(2-3):235-51
pubmed: 15871925
Brain Res. 1975 Nov 7;98(1):57-72
pubmed: 169967
Exp Neurol. 1984 Aug;85(2):316-35
pubmed: 6745377
Respir Physiol Neurobiol. 2011 Jul 31;177(2):176-82
pubmed: 21414423
J Appl Physiol (1985). 1985 Sep;59(3):969-78
pubmed: 4055582
J Physiol. 1985 Oct;367:45-56
pubmed: 4057106
Pediatr Res. 1990 Sep;28(3):196-8
pubmed: 2235113
Pediatr Res. 1986 Jul;20(7):658-61
pubmed: 3725464
J Neurophysiol. 2017 Feb 1;117(2):537-544
pubmed: 27832605
Brain Res. 1988 May 24;449(1-2):157-66
pubmed: 3395844
Respir Physiol. 1984 Dec;58(3):263-77
pubmed: 6528104
Am J Phys Med Rehabil. 2003 Oct;82(10):803-14
pubmed: 14508412
J Appl Physiol (1985). 1995 Nov;79(5):1640-9
pubmed: 8594024
Respir Physiol Neurobiol. 2009 Nov 30;169(2):94-101
pubmed: 19560562
Physiol Rep. 2018 Jul;6(13):e13786
pubmed: 29981218
J Appl Physiol (1985). 2000 Apr;88(4):1207-14
pubmed: 10749809
Respir Physiol Neurobiol. 2016 Jun;226:128-36
pubmed: 26506253
J Neurotrauma. 2013 Jun 15;30(12):1092-9
pubmed: 23534670
J Neurophysiol. 1988 Mar;59(3):1055-66
pubmed: 3367195
Pulm Pharmacol. 1996 Oct-Dec;9(5-6):343-7
pubmed: 9232673
J Neurotrauma. 2018 Feb 1;35(3):533-547
pubmed: 28844175
Spinal Cord. 2004 Jul;42(7):383-95
pubmed: 15037862
Brain Res. 1986 Aug 20;380(2):276-86
pubmed: 3756480
J Appl Physiol (1985). 1992 Oct;73(4):1626-36
pubmed: 1447114
Am Rev Respir Dis. 1981 Jul;124(1):41-4
pubmed: 7258818
Methods Mol Biol. 2016;1460:309-19
pubmed: 27492181
Physiol Rev. 2005 Apr;85(2):717-56
pubmed: 15788709
J Appl Physiol (1985). 1989 May;66(5):2196-205
pubmed: 2745285
Physiol Rev. 2001 Apr;81(2):929-69
pubmed: 11274347
Am Rev Respir Dis. 1987 Nov;136(5):1276-8
pubmed: 3674587
J Appl Physiol (1985). 1989 Jun;66(6):2539-45
pubmed: 2745316
Neurosci Lett. 1989 Feb 13;97(1-2):29-34
pubmed: 2521928
Neurosci Lett. 1988 Jun 17;89(1):63-8
pubmed: 3041320
J Appl Physiol (1985). 1996 Jun;80(6):1934-9
pubmed: 8806897
J Appl Physiol (1985). 2014 Dec 1;117(11):1308-16
pubmed: 25257864
J Appl Physiol (1985). 1988 Aug;65(2):852-62
pubmed: 2971642
J Physiol. 2009 Feb 15;587(Pt 4):713-9
pubmed: 19218620
Exp Neurol. 2012 Jun;235(2):539-52
pubmed: 22465264
Respir Physiol Neurobiol. 2012 Sep 30;183(3):186-92
pubmed: 22705013
Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1;309(1):L46-52
pubmed: 25934669
Respir Physiol Neurobiol. 2011 Oct 15;179(1):57-63
pubmed: 21763470
Brain Res. 1981 Feb 23;207(1):59-71
pubmed: 7470906
J Neurotrauma. 2016 Mar 1;33(5):500-9
pubmed: 26413840
Respir Physiol. 1993 Mar;91(2-3):183-93
pubmed: 8469843
Nature. 2016 Feb 18;530(7590):293-297
pubmed: 26855425
Respir Physiol Neurobiol. 2009 Mar 31;166(1):68-72
pubmed: 19429521
J Neurosci. 2003 Mar 15;23(6):2494-501
pubmed: 12657710
J Appl Physiol (1985). 1994 Jun;76(6):2552-60
pubmed: 7928883
Exp Physiol. 2016 Jul 1;101(7):883-94
pubmed: 27126607
Exp Neurol. 1998 Mar;150(1):143-52
pubmed: 9514833
Respir Physiol Neurobiol. 2015 May;210:14-21
pubmed: 25641347
Clin Chest Med. 1994 Dec;15(4):641-59
pubmed: 7867280
Respir Physiol Neurobiol. 2012 Jan 15;180(1):88-96
pubmed: 22063925
Respir Physiol Neurobiol. 2017 Dec;246:39-46
pubmed: 28790008
J Physiol. 1990 Sep;428:387-403
pubmed: 2231418
Respir Physiol Neurobiol. 2013 Aug 1;188(1):56-9
pubmed: 23632282
J Neurophysiol. 2017 Feb 1;117(2):545-555
pubmed: 27832610
Am Rev Respir Dis. 1990 Apr;141(4 Pt 1):926-32
pubmed: 2109559
J Neurotrauma. 2012 Dec 10;29(18):2748-60
pubmed: 23176637
Am Rev Respir Dis. 1986 Sep;134(3):488-92
pubmed: 3752705
J Appl Physiol (1985). 1998 Feb;84(2):562-8
pubmed: 9475866
Ann Fr Anesth Reanim. 1994;13(3):381-99
pubmed: 7992945
J Neurophysiol. 1965 May;28(3):599-620
pubmed: 5835487
Clin Chest Med. 1988 Jun;9(2):195-210
pubmed: 3292123
Exp Neurol. 1988 Jul;101(1):17-28
pubmed: 3391257
Exp Neurol. 2012 May;235(1):197-210
pubmed: 21963673
J Appl Physiol (1985). 2006 Mar;100(3):800-6
pubmed: 16269524