[Pulmonary tuberculosis: Radiological evolution of broncho-pulmonary lesions at the end of treatment].

Tuberculose pulmonaire : évolution radiologique des lésions broncho-pulmonaires en fin de traitement.

Journal

Revue des maladies respiratoires
ISSN: 1776-2588
Titre abrégé: Rev Mal Respir
Pays: France
ID NLM: 8408032

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 20 09 2017
accepted: 28 01 2018
pubmed: 22 9 2018
medline: 29 5 2019
entrez: 22 9 2018
Statut: ppublish

Résumé

To describe the residual broncho-pulmonary lesions and evaluate the role of CT scanning at the end of treatment of pulmonary tuberculosis. Analysis of the initial and end of treatment CT scans of 56 patients with pulmonary tuberculosis according to a reading grid including parenchymatous and airways lesions. The CT data at the end of treatment were analysed in relation to the clinical and microbiological data, and the original CT scan. Active lesions (thick walled cavities and/or centrilobular micronodules) persisted in 24 patients (43%) after a mean treatment period of 7 months. The persistence of these signs of activity was correlated with the initial presence of a cavitary syndrome (p=0.027), with predominant sub-segmentary bronchial involvement, with extensive micronodular spread (p=0.024) and with bronchiectasis (p=0.04). These residual lesions were not associated with an increased risk of relapse. The persistence of signs of activity on the CT scan at the end of treatment of tuberculosis do not necessarily correspond to an absence of cure but to a radiological delay. This imaging is nevertheless useful to make an assessment of any subsequent changes in the bronchial tree and to estimate the risk of later complications.

Identifiants

pubmed: 30236440
pii: S0761-8425(18)30267-5
doi: 10.1016/j.rmr.2018.08.005
pii:
doi:

Types de publication

Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

22-30

Informations de copyright

Copyright © 2018 SPLF. Published by Elsevier Masson SAS. All rights reserved.

Auteurs

F Méchaï (F)

Service des maladies infectieuses et tropicales, hôpital Avicenne, 125, route de Stalingrad, 93000 Bobigny, France; Inserm, IAME, UMR 1137, 75018 Paris, France. Electronic address: frederic.mechai@aphp.fr.

C Fock-Yee (C)

Service de radiologie, hôpital Avicenne, Bobigny, France.

D Bouvry (D)

Service de pneumologie, hôpital Avicenne, Bobigny, France.

A Raffetin (A)

Service des maladies infectieuses et tropicales, hôpital Avicenne, 125, route de Stalingrad, 93000 Bobigny, France.

O Bouchaud (O)

Service des maladies infectieuses et tropicales, hôpital Avicenne, 125, route de Stalingrad, 93000 Bobigny, France; Laboratoire éducations et pratiques de santé EA 3412, université Paris 13, Bobigny, France.

M Brauner (M)

Service de radiologie, hôpital Avicenne, Bobigny, France.

P Y Brillet (PY)

Service de radiologie, hôpital Avicenne, Bobigny, France.

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Classifications MeSH