SIU-ICUD recommendations on bladder cancer: systemic therapy for metastatic bladder cancer.


Journal

World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 06 08 2018
accepted: 10 09 2018
pubmed: 22 9 2018
medline: 23 5 2019
entrez: 22 9 2018
Statut: ppublish

Résumé

The SIU (Société Internationale d'Urologie)-ICUD (International Consultation on Urologic Diseases) working group on systemic therapy for metastatic bladder cancer has summarized the most recent findings on the aforementioned topic and came to conclusions and recommendations according to the evidence published. In Europe and the United States, treatment for metastatic UC has changed a great deal recently, mainly involving a move from chemotherapy to immune checkpoint blockers. This is particularly true in platinum-refractory disease, where supportive randomized data exist. Five checkpoint blockers have been approved in this setting by the FDA: avelumab, atezolizumab, durvalumab, nivolumab, and pembrolizumab. Nivolumab, pembrolizumab, and atezolizumab have been approved in Europe.

Identifiants

pubmed: 30238401
doi: 10.1007/s00345-018-2486-1
pii: 10.1007/s00345-018-2486-1
pmc: PMC7515768
mid: NIHMS1628286
doi:

Substances chimiques

Antibodies, Monoclonal 0
Antibodies, Monoclonal, Humanized 0
Antineoplastic Agents, Immunological 0
Deoxycytidine 0W860991D6
durvalumab 28X28X9OKV
Nivolumab 31YO63LBSN
atezolizumab 52CMI0WC3Y
Vinblastine 5V9KLZ54CY
Doxorubicin 80168379AG
Carboplatin BG3F62OND5
pembrolizumab DPT0O3T46P
avelumab KXG2PJ551I
Paclitaxel P88XT4IS4D
Cisplatin Q20Q21Q62J
Methotrexate YL5FZ2Y5U1
Gemcitabine 0

Types de publication

Journal Article Practice Guideline Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

95-105

Subventions

Organisme : NCI NIH HHS
ID : P30 CA014089
Pays : United States

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Auteurs

Axel S Merseburger (AS)

Department of Urology, Campus Lübeck, University Hospital Schleswig-Holstein, Lübeck, Germany.

Andrea B Apolo (AB)

Center for Cancer Research, National Cancer Institute, NIH Maryland, Bethesda, USA.

Simon Chowdhury (S)

Guy's and St, Thomas' Hospital, Great Maze Pond, London, UK.

Noah M Hahn (NM)

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, USA.

Matthew D Galsky (MD)

Division of Hematology and Medical Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA.

Matthew I Milowsky (MI)

Division of Hematology/Oncology, Department of Medicine, University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.

Daniel Petrylak (D)

Yale Cancer Center, New Haven, CT, USA.

Tom Powles (T)

Barts Cancer Institute, London, USA.

David I Quinn (DI)

Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.

Jonathan E Rosenberg (JE)

Memorial Sloan Kettering Cancer Center, New York, USA.

Arlene Siefker-Radtke (A)

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Guru Sonpavde (G)

Department of Medical Oncology, Bladder Cancer Center, Dana Farber Cancer Institute, Boston, MA, USA.

Cora N Sternberg (CN)

Department of Medical Oncology, San Camillo Forlanini Hospital, Rome, Italy. cnsternberg@corasternberg.com.

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Classifications MeSH