Effect of CBX7 deficiency on the socket healing after tooth extractions.
Animals
Bone Density
Bone Resorption
/ pathology
Male
Mice, Knockout
Neovascularization, Physiologic
Osteoblasts
/ metabolism
Osteoclasts
/ metabolism
Osteogenesis
/ drug effects
Polycomb Repressive Complex 1
/ deficiency
Time Factors
Tooth Extraction
Tooth Socket
/ blood supply
Wound Healing
/ drug effects
CBX7
Histomorphometric analysis
Mice
Socket healing
Tooth extraction
Journal
Journal of bone and mineral metabolism
ISSN: 1435-5604
Titre abrégé: J Bone Miner Metab
Pays: Japan
ID NLM: 9436705
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
21
07
2017
accepted:
05
09
2018
pubmed:
22
9
2018
medline:
31
8
2019
entrez:
22
9
2018
Statut:
ppublish
Résumé
CBX7 is shown to down-regulate the expression of osteopontin (OPN) that is associated with osteoblast function. Here, we studied the role of CBX7 in the wound healing of tooth extraction socket in which osteoblast activity is critical via comparison between CBX7-knockout (CBX7
Identifiants
pubmed: 30238429
doi: 10.1007/s00774-018-0958-4
pii: 10.1007/s00774-018-0958-4
doi:
Substances chimiques
Cbx7 protein, mouse
0
Polycomb Repressive Complex 1
EC 2.3.2.27
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
584-593Subventions
Organisme : the National Natural Science Foundation of China
ID : 81670966
Organisme : The Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
ID : PAPD
Organisme : The Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
ID : 2014-37
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