The Emergency Medicine Specimen Bank: An Innovative Approach To Biobanking In Acute Care.
Journal
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
ISSN: 1553-2712
Titre abrégé: Acad Emerg Med
Pays: United States
ID NLM: 9418450
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
05
07
2018
revised:
07
09
2018
accepted:
17
09
2018
pubmed:
22
9
2018
medline:
11
4
2020
entrez:
22
9
2018
Statut:
ppublish
Résumé
The Emergency Medicine Specimen Bank (EMSB) was developed to facilitate precision medicine in acute care. The EMSB is a biorepository of clinical health data and biospecimens collected from all adult English- or Spanish-speaking individuals who are able and willing to provide consent and are treated at the UCHealth-University of Colorado Hospital Emergency Department. The EMSB is the first acute care biobank that seeks to enroll all patients, with all conditions who present to the ED. Acute care biobanking presents many challenges that are unique to acute care settings such as providing informed consent in a uniquely stressful and fast-paced environment and collecting, processing, and storing samples for tens of thousands of patients per year. Here, we describe the process by which the EMSB overcame these challenges and was integrated into clinical workflow allowing for operation 24 hours a day, 7 days a week at a reasonable cost. Other institutions can implement this template, further increasing the power of biobanking research to inform treatment strategies and interventions for common and uncommon phenotypes in acute care settings.
Identifiants
pubmed: 30239069
doi: 10.1111/acem.13620
pmc: PMC6428625
mid: NIHMS989683
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
639-647Subventions
Organisme : University of Colorado Department of Emergency Medicine Research Pilot Grant
Pays : International
Organisme : NCATS NIH HHS
ID : UL1 TR002535
Pays : United States
Organisme : UCHealth
Pays : International
Organisme : NIGMS NIH HHS
ID : K23 GM110516
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM124939
Pays : United States
Informations de copyright
© 2018 by the Society for Academic Emergency Medicine.
Références
Thromb Haemost. 2010 Sep;104(3):471-84
pubmed: 20664898
Expert Opin Drug Metab Toxicol. 2018 Apr;14(4):435-446
pubmed: 29528249
Rapid Commun Mass Spectrom. 2017 Sep 15;31(17):1445-1452
pubmed: 28586533
JAMA. 2015 Jun 2;313(21):2119-20
pubmed: 25928209
Acad Emerg Med. 2016 Oct;23(10):1097-1106
pubmed: 27288269
PLoS Biol. 2017 Jul 25;15(7):e2002654
pubmed: 28742850
Fed Regist. ;82(12):7149-274
pubmed: 28106360
Annu Rev Pharmacol Toxicol. 2016;56:211-28
pubmed: 26514206
Crit Care. 2017 Dec 28;21(Suppl 3):314
pubmed: 29297399
Curr Treat Options Oncol. 2017 May;18(5):27
pubmed: 28439798
Shock. 2015 Sep;44(3):200-8
pubmed: 26009817
Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1357-66
pubmed: 19018689
J Proteome Res. 2013 Dec 6;12(12):5383-94
pubmed: 24063748
Genomics Inform. 2012 Jun;10(2):117-22
pubmed: 23105939