Necrotizing Otitis Externa-Analysis of 83 Cases: Clinical Findings and Course of Disease.
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents
/ therapeutic use
Cephalosporins
/ therapeutic use
Disease Progression
Female
Hospitalization
Humans
Male
Middle Aged
Otitis Externa
/ drug therapy
Pseudomonas Infections
/ drug therapy
Pseudomonas aeruginosa
/ isolation & purification
Quinolones
/ therapeutic use
Retrospective Studies
Tertiary Care Centers
Treatment Outcome
Journal
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
ISSN: 1537-4505
Titre abrégé: Otol Neurotol
Pays: United States
ID NLM: 100961504
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
pubmed:
22
9
2018
medline:
14
1
2020
entrez:
22
9
2018
Statut:
ppublish
Résumé
Evaluate the relationship between clinical findings and course of disease among patients with necrotizing otitis externa (NOE). Retrospective case series review. Tertiary referral center. Adult patients with no previous history of chronic ear disease, hospitalized due to NOE between the years 1990 to 2015. 1) Duration of hospitalization and 2) necessity for surgery. Eighty-one patients were included in the study, corresponding to 83 effected ears. Thirty-two patients (38.5%) were hospitalized longer than 20 days and 20 patients (24.0%) underwent surgery. Otalgia was the most common complaint (n = 71, 85.5%). Pseudomonas Aeruginosa (PA) was the most common isolated bacteria (n = 40, 48.1%). Shifting incidence of culture results was noted, as rates of PA NOE decreased and rates of sterile culture and fungal NOE increased. Duration of complaints and presence of aural discharge at admission were associated with prolonged hospitalization (p = 0.010, p = 0.011, respectively). Advanced age, duration of hospitalization, and rates of readmission were associated with surgery (p = 0.037, p < 0.001, p < 0.001 respectively). Duration of complaints and presence of aural discharge may indicate advanced NOE and require longer in-hospital treatment. Elderly patients are at increased risk for conservative treatment failure and are more likely to require surgery. With shifting incidence of pathogens, a wider empirical treatment covering nontraditional pathogens should be considered.
Identifiants
pubmed: 30239427
doi: 10.1097/MAO.0000000000001986
doi:
Substances chimiques
Anti-Bacterial Agents
0
Cephalosporins
0
Quinolones
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
56-62Commentaires et corrections
Type : CommentIn
Type : CommentIn