Enamel matrix derivative for the treatment of partially contained intrabony defects: 12-month results.
Alveolar Bone Loss
/ surgery
Animals
Bone Regeneration
Bone Substitutes
/ therapeutic use
Cattle
Chronic Periodontitis
/ surgery
Dental Enamel Proteins
/ therapeutic use
Follow-Up Studies
Furcation Defects
/ surgery
Guided Tissue Regeneration, Periodontal
/ methods
Humans
Periodontal Attachment Loss
Periodontal Pocket
Treatment Outcome
Bone regeneration
enamel matrix derivative
periodontal diseases
periodontal regeneration
periodontitis
Journal
Australian dental journal
ISSN: 1834-7819
Titre abrégé: Aust Dent J
Pays: Australia
ID NLM: 0370612
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
accepted:
20
09
2018
pubmed:
27
9
2018
medline:
4
12
2019
entrez:
27
9
2018
Statut:
ppublish
Résumé
The aim of the study was to evaluate the use of enamel matrix derivative (EMD) alone or in association with deproteinized bovine bone mineral (DBBM) for the treatment of partially contained intrabony defects. A total of 20 two-walled intrabony defects belonging to nine patients were included. Ten defects were treated with EMD alone (test group 1) and the other 10 were treated with EMD and DBBM (test group 2), applying either modified papilla preservation technique or simplified papilla preservation technique. Twelve months after surgery, in the test group 1, PD was 2.8 ± 0.8 mm, REC was 2.3 ± 2.4 mm and CAL was 5.0 ± 2.8 mm, significantly reduced from baseline values (P < 0.05). Likewise, in test group 2, PD, REC and CAL reduced to 3.0 ± 0.7 mm, 3.9 ± 1.5 mm and 6.9 ± 1.1 mm respectively, from baseline values at 12 months (P < 0.05). No significant differences between groups were found. The results showed that the use of EMD alone and the use of a combination of EMD and DBBM for the treatment of partially contained defects showed comparable clinical and radiographic outcomes after 12 months.
Sections du résumé
BACKGROUND
The aim of the study was to evaluate the use of enamel matrix derivative (EMD) alone or in association with deproteinized bovine bone mineral (DBBM) for the treatment of partially contained intrabony defects.
METHODS
A total of 20 two-walled intrabony defects belonging to nine patients were included. Ten defects were treated with EMD alone (test group 1) and the other 10 were treated with EMD and DBBM (test group 2), applying either modified papilla preservation technique or simplified papilla preservation technique.
RESULTS
Twelve months after surgery, in the test group 1, PD was 2.8 ± 0.8 mm, REC was 2.3 ± 2.4 mm and CAL was 5.0 ± 2.8 mm, significantly reduced from baseline values (P < 0.05). Likewise, in test group 2, PD, REC and CAL reduced to 3.0 ± 0.7 mm, 3.9 ± 1.5 mm and 6.9 ± 1.1 mm respectively, from baseline values at 12 months (P < 0.05). No significant differences between groups were found.
CONCLUSIONS
The results showed that the use of EMD alone and the use of a combination of EMD and DBBM for the treatment of partially contained defects showed comparable clinical and radiographic outcomes after 12 months.
Substances chimiques
Bone Substitutes
0
Dental Enamel Proteins
0
enamel matrix proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
27-34Informations de copyright
© 2018 Australian Dental Association.