First-in-man experience of the Versi Retriever in acute ischemic stroke.


Journal

Journal of neurointerventional surgery
ISSN: 1759-8486
Titre abrégé: J Neurointerv Surg
Pays: England
ID NLM: 101517079

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 25 04 2018
revised: 13 07 2018
accepted: 21 07 2018
pubmed: 29 9 2018
medline: 10 4 2019
entrez: 29 9 2018
Statut: ppublish

Résumé

To describe our initial experience with the Versi Retriever for mechanical thrombectomy in patients with acute ischemic stroke. This study is a single-center, single-arm, first-in-man registry under institutional review board control to evaluate the efficacy and safety of the new stent retriever, the Versi Retriever. Patients with acute ischemic stroke were consecutively enrolled between September and November 2017. The clinical and procedural data were retrospectively analyzed. The angiographic result after the procedure was self-graded based on the Thrombolysis in Cerebral Infarction (TICI) scale by each operator. Eleven patients with a mean age of 69.4 years were treated with the Versi Retriever. Median National Institutes of Health Stroke Scale score on admission was 16 (IQR 10-34). The occluded vessel was located in the anterior circulation in 81.8%. Revascularization rates of TICI 2b-3 and TICI 3 at final angiogram were achieved in 100% and 63.6%, respectively. A favorable functional outcome (modified Rankin Scale 0-2) at 90 days was obtained in 72.7%. No symptomatic intracranial hemorrhage occurred and no procedure-related complication was observed. Our initial experience suggests that the Versi Retriever is a safe and effective stent retriever for mechanical thrombectomy in patients with acute ischemic stroke. NCT03366818.

Identifiants

pubmed: 30262657
pii: neurintsurg-2018-014040
doi: 10.1136/neurintsurg-2018-014040
doi:

Substances chimiques

Alloys 0
nitinol 2EWL73IJ7F

Banques de données

ClinicalTrials.gov
['NCT03366818']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

296-299

Informations de copyright

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: NS has been a consultant for Cerenovus, Medtronic, Microvention, Neurovasc, Penumbra and Stryker; NK has been a consultant for Neurovasc; ST holds stock in Neurovasc and has been a consultant for Cerenovus, Medtronic, Neurovasc and Stryker.

Auteurs

Nobuyuki Sakai (N)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Hirotoshi Imamura (H)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Hidemitsu Adachi (H)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Shoichi Tani (S)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

So Tokunaga (S)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Takayuki Funatsu (T)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Keita Suzuki (K)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Hiromasa Adachi (H)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Natsuhi Sasaki (N)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Shuhei Kawabata (S)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Ryo Akiyama (R)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Kazufumi Horiuchi (K)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Nobuyuki Ohara (N)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Tomoyuki Kono (T)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Satoru Fujiwara (S)

Department of Neurosurgery, Neurology and Comprehensive Stroke Center, Kobe City Medical Center General Hospital, Kobe, Japan.

Naoki Kaneko (N)

Division of Interventional Neuroradiology, Ronald Reagan UCLA Medical Center, Los Angeles, USA.

Satoshi Tateshima (S)

Division of Interventional Neuroradiology, Ronald Reagan UCLA Medical Center, Los Angeles, USA.

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Classifications MeSH