A simplified framework to optimize MRI contrast preparation.
Aging
Algorithms
Alzheimer Disease
/ diagnostic imaging
Animals
Brain
/ diagnostic imaging
Computer Simulation
Contrast Media
/ pharmacology
Corpus Callosum
/ diagnostic imaging
Female
Gray Matter
/ diagnostic imaging
Hippocampus
/ diagnostic imaging
Humans
Magnetic Resonance Imaging
Magnetics
Models, Theoretical
Multiple Sclerosis
/ diagnostic imaging
Phantoms, Imaging
Rats
Thalamus
/ diagnostic imaging
Bloch equations
contrast
optimal control
preparation pulses
rat brain
white matter
Journal
Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
04
10
2018
revised:
28
05
2018
accepted:
01
06
2018
pubmed:
29
9
2018
medline:
31
12
2019
entrez:
29
9
2018
Statut:
ppublish
Résumé
This article proposes a rigorous optimal control framework for the design of preparation schemes that optimize MRI contrast based on relaxation time differences. Compared to previous optimal contrast preparation schemes, a drastic reduction of the optimization parameter number is performed. The preparation scheme is defined as a combination of several block pulses whose flip angles, phase terms and inter-pulse delays are optimized to control the magnetization evolution. The proposed approach reduces the computation time of This approach proposes key advances for the design of optimal contrast preparation sequences, that emphasize their ability to generate non-standard contrasts, their potential benefit in a clinical context, and their straightforward applicability on any MR system.
Substances chimiques
Contrast Media
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
424-438Subventions
Organisme : ANR-DFG Explosys
ID : ANR-14-CE35-0013-01
Pays : International
Organisme : ANR-DFG Explosys
ID : GL203/9-1
Pays : International
Organisme : TUM Institute for Advanced Study, the German Excellence Initiative, the E.U. Seventh Framework Programme
ID : 291763
Pays : International
Organisme : LABEX PRIMES
ID : ANR-11-LABX-0063
Pays : International
Organisme : LABEX PRIMES
ID : ANR-11-IDEX-0007
Pays : International
Informations de copyright
© 2018 International Society for Magnetic Resonance in Medicine.