Detection of amyloid β oligomers toward early diagnosis of Alzheimer's disease.

Alzheimer Disease / diagnosis Amyloid beta-Peptides / analysis Antibodies, Monoclonal, Humanized / chemistry Brain / metabolism Early Diagnosis Enzyme-Linked Immunosorbent Assay Humans Limit of Detection Peptide Fragments / analysis Quartz Crystal Microbalance Techniques

Journal

Analytical biochemistry
ISSN: 1096-0309
Titre abrégé: Anal Biochem
Pays: United States
ID NLM: 0370535

Informations de publication

Date de publication:
01 02 2019
Historique:
received: 30 01 2018
revised: 28 08 2018
accepted: 12 09 2018
pubmed: 30 9 2018
medline: 28 11 2019
entrez: 30 9 2018
Statut: ppublish

Résumé

Amyloid β (Aβ) peptide accumulation in the brain is considered to be one of the hallmarks of Alzheimer's disease. Here, we compare two analytical techniques for detecting neurotoxic Aβ

Identifiants

DOI: 10.1016/j.ab.2018.09.011 PMID: 30267709
pubmed: 30267709
pii: S0003-2697(18)30440-8
doi: 10.1016/j.ab.2018.09.011
pii:
doi:

Substances chimiques

Amyloid beta-Peptides 0
Antibodies, Monoclonal, Humanized 0
Peptide Fragments 0
amyloid beta-protein (1-42) 0
bapineuzumab NC11WKO35D

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

40-45

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Soyoon Sarah Hwang (SS)

Department of Chemistry, Tufts University, 62 Talbot Ave, Medford, MA, 02155, USA; Sackler School of Graduate Biomedical Sciences, Graduate Program in Biochemistry, Tufts University School of Medicine, Boston, MA, 02111, USA.

Hon Chan (H)

Howard P. Isermann Department of Biological and Chemical Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.

Mirco Sorci (M)

Howard P. Isermann Department of Biological and Chemical Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.

James Van Deventer (J)

Department of Chemical Engineering and Bioengineering, Massachusetts Institute of Technology, 500 Main St, Cambridge, MA, 02139, USA.

Dane Wittrup (D)

Department of Chemical Engineering and Bioengineering, Massachusetts Institute of Technology, 500 Main St, Cambridge, MA, 02139, USA.

Georges Belfort (G)

Howard P. Isermann Department of Biological and Chemical Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA. Electronic address: belfog@rpi.edu.

David Walt (D)

Department of Chemistry, Tufts University, 62 Talbot Ave, Medford, MA, 02155, USA. Electronic address: dwalt@bwh.harvard.edu.

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Peptides bêta-amyloïdes › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps monoclonaux › Anticorps monoclonaux humanisés › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Diagnostic › Diagnostic précoce › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Dosage immunologique › Techniques d'immunoadsorption › Test ELISA › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Sensibilité et spécificité › Limite de détection › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Fragments peptidiques › Detection of amyloid β oligomers toward early...
questionsmedicales.fr › Techniques d'investigation › Poids et mesures › Techniques de microbalance à cristal de quartz › Detection of amyloid β oligomers toward early...