Association Between High Levels of Hepatitis B Core Antibody and Seroclearance of Hepatitis B e Antigen in Individuals With Chronic Hepatitis B Virus Infection.

DNA, Viral / analysis Follow-Up Studies Genotype Hepatitis B Antibodies / immunology Hepatitis B Surface Antigens / immunology Hepatitis B virus / genetics Hepatitis B, Chronic / metabolism Humans Immunoenzyme Techniques Prognosis Retrospective Studies Time Factors Viral Load

Journal

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
ISSN: 1542-7714
Titre abrégé: Clin Gastroenterol Hepatol
Pays: United States
ID NLM: 101160775

Informations de publication

Date de publication:
06 2019
Historique:
received: 31 07 2018
revised: 12 09 2018
accepted: 17 09 2018
pubmed: 30 9 2018
medline: 21 10 2020
entrez: 30 9 2018
Statut: ppublish

Résumé

For chronic hepatitis B patients, hepatitis B e antigen (HBeAg) seroclearance signals a transition from an immunologically active phase to an inactive carrier state with a reduction in hepatitis B virus (HBV) DNA levels and a reduced risk of hepatocellular carcinoma (HCC).

Identifiants

DOI: 10.1016/j.cgh.2018.09.037 PMID: 30267868
pubmed: 30267868
pii: S1542-3565(18)31028-0
doi: 10.1016/j.cgh.2018.09.037
pii:
doi:

Substances chimiques

DNA, Viral 0
Hepatitis B Antibodies 0
Hepatitis B Surface Antigens 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1413-1415

Informations de copyright

Copyright © 2019 AGA Institute. Published by Elsevier Inc. All rights reserved.

Auteurs

Jessica Liu (J)

Genomics Research Center, Academia Sinica, Taipei, Taiwan.

Hui-Han Hu (HH)

Genomics Research Center, Academia Sinica, Taipei, Taiwan.

Chia-Ling Chang (CL)

Genomics Research Center, Academia Sinica, Taipei, Taiwan.

Chin-Lan Jen (CL)

Genomics Research Center, Academia Sinica, Taipei, Taiwan.

Mei-Hsuan Lee (MH)

Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.

Sheng-Nan Lu (SN)

Department of Gastroenterology, Chang-Gung Memorial Hospital, Kaohsiung, Taiwan.

Li-Yu Wang (LY)

MacKay College of Medicine, New Taipei City, Taiwan.

Quan Yuan (Q)

School of Public Health, Xiamen University, Xiamen, Fujian, China.

Ning-Shao Xia (NS)

School of Public Health, Xiamen University, Xiamen, Fujian, China.

Masaya Sugiyama (M)

The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan.

Nao Nishida (N)

The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan.

Masashi Mizokami (M)

The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan; Department of Hepatitis and Immunology, Nagoya City University Graduate School of Medical Science, Nagoya, Japan.

Chien-Jen Chen (CJ)

Academia Sinica, Taipei, Taiwan.

Pei-Jer Chen (PJ)

Division of Gastroenterology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan.

Hwai-I Yang (HI)

Genomics Research Center, Academia Sinica, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address: hiyang@gate.sinica.edu.tw.

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN viral › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études de suivi › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps antiviraux › Anticorps de l'hépatite › Anticorps de l'hépatite B › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes viraux › Antigènes d'hépatite virale › Antigènes de l'hépatite virale B › Antigènes de surface du virus de l'hépatite B › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Virus › Virus de l'hépatite › Hepadnaviridae › Orthohepadnavirus › Virus de l'hépatite B › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Hépatite chronique › Hépatite B chronique › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Dosage immunologique › Techniques immunoenzymatiques › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Diagnostic › Pronostic › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Phénomènes physiques › Temps › Facteurs temps › Association Between High Levels of Hepatitis B...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Charge virale › Association Between High Levels of Hepatitis B...