Optimal Management of Malignant Polyps, From Endoscopic Assessment and Resection to Decisions About Surgery.


Journal

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
ISSN: 1542-7714
Titre abrégé: Clin Gastroenterol Hepatol
Pays: United States
ID NLM: 101160775

Informations de publication

Date de publication:
07 2019
Historique:
received: 28 06 2018
revised: 28 08 2018
accepted: 16 09 2018
pubmed: 1 10 2018
medline: 22 10 2020
entrez: 1 10 2018
Statut: ppublish

Résumé

Colorectal cancer is defined clinically as invasion of dysplastic cells into the submucosa. Lesions with submucosal invasion but without invasion into the muscularis propria are generally called malignant polyps. A stepwise approach produces optimal management of malignant polyps (including polypoid and flat/depressed lesions). The first step is to avoid endoscopic resection of non-pedunculated lesions with endoscopic features that predict deep submucosal invasion. Lesions without such features are candidates for endoscopic resection. The second step is to assess candidates for endoscopic resection for features that predict an increased risk of superficial submucosal invasion. Such lesions should be considered for en bloc endoscopic excision if feasible. The third step is giving patients with endoscopically resected malignant polyps good advice regarding whether to undergo adjuvant therapy, usually surgery. We review the endoscopic and histologic criteria that guide clinicians through these steps.

Identifiants

pubmed: 30268567
pii: S1542-3565(18)31072-3
doi: 10.1016/j.cgh.2018.09.040
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1428-1437

Informations de copyright

Copyright © 2019 AGA Institute. Published by Elsevier Inc. All rights reserved.

Auteurs

Douglas K Rex (DK)

Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address: drex@iupui.edu.

Aasma Shaukat (A)

Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota; Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota School of Medicine, Minneapolis, Minnesota.

Michael B Wallace (MB)

Department of Gastroenterology and Hepatology, Mayo Clinic Jacksonville, Jacksonville, Florida.

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