Development and commercialization of reduced lignin alfalfa.
Journal
Current opinion in biotechnology
ISSN: 1879-0429
Titre abrégé: Curr Opin Biotechnol
Pays: England
ID NLM: 9100492
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
20
06
2018
revised:
07
09
2018
accepted:
11
09
2018
pubmed:
1
10
2018
medline:
5
11
2019
entrez:
1
10
2018
Statut:
ppublish
Résumé
Reducing lignin content in forage legumes can improve digestibility and, correspondingly, animal performance, and alfalfa (Medicago sativa) is the first genetically engineered crop commercialized for improved forage digestibility. Lignin reduction was achieved by downregulating the gene encoding caffeoyl-CoA 3-O-methyltransferase (CCoAOMT), and development of the commercial product, branded as HarvXtra, required the coordination of two research institutions and two companies, and more than 15 years of research and field trials. Lignin modification has positive impacts on forage management. Future developments will likely stack lignin modification with additional forage quality traits.
Identifiants
pubmed: 30268938
pii: S0958-1669(18)30075-2
doi: 10.1016/j.copbio.2018.09.003
pii:
doi:
Substances chimiques
Lignin
9005-53-2
Methyltransferases
EC 2.1.1.-
caffeoyl-CoA O-methyltransferase
EC 2.1.1.104
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
48-54Informations de copyright
Copyright © 2018 Elsevier Ltd. All rights reserved.