Neural correlates of developing theory of mind competence in early childhood.
Functional connectivity
Resting-state fMRI
Right temporo-parietal junction
Theory of mind
Young children
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
01 01 2019
01 01 2019
Historique:
received:
11
06
2018
revised:
23
09
2018
accepted:
26
09
2018
pubmed:
3
10
2018
medline:
7
3
2019
entrez:
2
10
2018
Statut:
ppublish
Résumé
Theory of mind (ToM) encompasses a range of abilities that show different developmental time courses. However, relatively little work has examined the neural correlates of ToM during early childhood. In this study, we investigated the neural correlates of ToM in typically developing children aged 4-8 years using resting-state functional magnetic resonance imaging. We calculated whole-brain functional connectivity with the right temporo-parietal junction (RTPJ), a core region involved in ToM, and examined its relation to children's early, basic, and advanced components of ToM competence assessed by a parent-report measure. Total ToM and both basic and advanced ToM components, but not early, consistently showed a positive correlation with connectivity between RTPJ and posterior cingulate cortex/precuneus; advanced ToM was also correlated with RTPJ to left TPJ connectivity. However, early and advanced ToM components showed negative correlation with the right inferior/superior parietal lobe, suggesting that RTPJ network differentiation is also related to ToM abilities. We confirmed and extended these results using a Bayesian modeling approach demonstrating significant relations between multiple nodes of the mentalizing network and ToM abilities, with no evidence for differences in relations between ToM components. Our data provide new insights into the neural correlates of multiple aspects of ToM in early childhood and may have implications for both typical and atypical development of ToM.
Identifiants
pubmed: 30273714
pii: S1053-8119(18)31951-7
doi: 10.1016/j.neuroimage.2018.09.079
pmc: PMC6230512
mid: NIHMS1509365
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
707-716Subventions
Organisme : NICHD NIH HHS
ID : R01 HD079518
Pays : United States
Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.
Références
Dev Cogn Neurosci. 2011 Jan;1(1):7-21
pubmed: 22436416
J Cogn Neurosci. 2009 Jun;21(6):1179-92
pubmed: 18702587
Neuroimage. 2015 Jan 15;105:536-51
pubmed: 25462692
Soc Cogn Affect Neurosci. 2006 Dec;1(3):229-34
pubmed: 18985110
Neuroinformatics. 2019 Oct;17(4):515-545
pubmed: 30649677
J Cogn Neurosci. 1997 Fall;9(5):648-63
pubmed: 23965122
Cognition. 1983 Jan;13(1):103-28
pubmed: 6681741
Neuroimage. 2015 Nov 15;122:222-32
pubmed: 26241683
Nat Rev Neurosci. 2006 Apr;7(4):268-77
pubmed: 16552413
Child Dev. 2012 Nov;83(6):1853-68
pubmed: 22849953
Percept Mot Skills. 2006 Jun;102(3):819-35
pubmed: 16916162
Dev Cogn Neurosci. 2019 Dec;40:100705
pubmed: 31593908
Neuroinformatics. 2016 Jul;14(3):339-51
pubmed: 27075850
Brain Struct Funct. 2015 Mar;220(2):1031-49
pubmed: 24399179
Neuroimage. 2008 Jul 1;41(3):903-13
pubmed: 18424084
PLoS One. 2017 Jan 10;12(1):e0169510
pubmed: 28072823
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3370-E3371
pubmed: 28420798
Neuroimage. 2002 Jul;16(3 Pt 1):814-21
pubmed: 12169265
Neuroimage. 2017 Nov 1;161:9-18
pubmed: 28807871
Front Hum Neurosci. 2013 Jul 05;7:340
pubmed: 23847509
Neuroimage. 2007 Aug 1;37(1):90-101
pubmed: 17560126
Nat Commun. 2018 Mar 12;9(1):1027
pubmed: 29531321
Child Dev. 2005 Mar-Apr;76(2):502-17
pubmed: 15784096
Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12569-74
pubmed: 18723676
Cereb Cortex. 2016 Aug;26(8):3544-52
pubmed: 27230216
Philos Trans R Soc Lond B Biol Sci. 2003 Mar 29;358(1431):459-73
pubmed: 12689373
Trends Cogn Sci. 2003 Feb;7(2):77-83
pubmed: 12584026
PeerJ. 2017 Jul 7;5:e3544
pubmed: 28698825
Neurosci Biobehav Rev. 2016 Jun;65:276-91
pubmed: 27073047
Neuroimage. 2003 Aug;19(4):1835-42
pubmed: 12948738
Hum Brain Mapp. 2009 Aug;30(8):2313-35
pubmed: 19034900
PLoS One. 2013 Jul 04;8(7):e68910
pubmed: 23861951
Dev Cogn Neurosci. 2016 Jun;19:58-69
pubmed: 26900967
Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13040-5
pubmed: 19620724
Child Dev. 2001 May-Jun;72(3):655-84
pubmed: 11405571
Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11832-5
pubmed: 11562505
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):676-82
pubmed: 11209064
Psychol Sci. 2006 Aug;17(8):692-9
pubmed: 16913952
Child Dev. 2009 Jul-Aug;80(4):1147-62
pubmed: 19630899
Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9673-8
pubmed: 15976020
Comput Biomed Res. 1996 Jun;29(3):162-73
pubmed: 8812068
Neuroimage. 2013 Aug 1;76:439-41
pubmed: 22440651
Neuron. 2006 May 18;50(4):531-4
pubmed: 16701204
Neuroimage. 2014 Jan 1;84:320-41
pubmed: 23994314
Neuropsychologia. 2000;38(1):11-21
pubmed: 10617288
Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7900-5
pubmed: 27357684
J Cogn Neurosci. 2006 Sep;18(9):1586-94
pubmed: 16989558
J Cogn Neurosci. 2009 Mar;21(3):489-510
pubmed: 18510452
Trends Cogn Sci. 2015 Feb;19(2):65-72
pubmed: 25496670
Biol Lett. 2010 Aug 23;6(4):540-3
pubmed: 20106861
Hum Brain Mapp. 2009 Mar;30(3):829-58
pubmed: 18381770
PLoS One. 2012;7(2):e30920
pubmed: 22319593
Neurosci Biobehav Rev. 2014 May;42:9-34
pubmed: 24486722
Neuroimage. 2013 Jan 1;64:240-56
pubmed: 22926292
Neuroimage. 2007 Apr 15;35(3):1378-84
pubmed: 17376703
Neuroimage. 2011 Feb 1;54(3):2033-44
pubmed: 20851191
Child Dev. 2009 Jul-Aug;80(4):1197-209
pubmed: 19630902
eNeuro. 2016 Apr 29;3(2):
pubmed: 27280153
Neuroimage. 2016 Mar;128:116-124
pubmed: 26690809
Neuropsychologia. 2010 Jul;48(9):2658-64
pubmed: 20470808
Cereb Cortex. 2012 Aug;22(8):1894-903
pubmed: 21955921
Trends Cogn Sci. 2013 Jul;17(7):328-36
pubmed: 23790322
Neuroimage. 2012 Mar;60(1):623-32
pubmed: 22233733
Neuropsychologia. 2005;43(10):1391-9
pubmed: 15936784
Neuroimage. 2012 Jan 2;59(1):431-8
pubmed: 21810475
Neuroimage. 2012 Feb 1;59(3):2142-54
pubmed: 22019881
Soc Cogn Affect Neurosci. 2012 Jan;7(1):53-63
pubmed: 21467048
Child Dev. 2004 Mar-Apr;75(2):523-41
pubmed: 15056204
Neuroimage. 2014 May 1;91:412-9
pubmed: 24412399
Soc Neurosci. 2006;1(3-4):245-58
pubmed: 18633791
Brain. 2014 Jan;137(Pt 1):12-32
pubmed: 23869106
Neuropsychologia. 2007 Apr 8;45(7):1522-32
pubmed: 17208260
J Neurophysiol. 2011 Sep;106(3):1125-65
pubmed: 21653723
Magn Reson Med. 1996 Mar;35(3):346-55
pubmed: 8699946
Front Hum Neurosci. 2013 Sep 17;7:493
pubmed: 24062654
J Autism Dev Disord. 2012 Mar;42(3):327-41
pubmed: 21484516
Nat Methods. 2011 Jun 26;8(8):665-70
pubmed: 21706013