[Multidrug-resistant bacteria in animals and humans].
Multiresistente Erreger bei Tier und Mensch.
ESBL
Germany
Livestock
MRSA
Zoonosis
Journal
Medizinische Klinik, Intensivmedizin und Notfallmedizin
ISSN: 2193-6226
Titre abrégé: Med Klin Intensivmed Notfmed
Pays: Germany
ID NLM: 101575086
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
10
11
2017
accepted:
13
08
2018
revised:
27
07
2018
pubmed:
3
10
2018
medline:
25
9
2020
entrez:
3
10
2018
Statut:
ppublish
Résumé
The increasing burden of antimicrobial-resistant bacteria causes morbidity and mortality, especially among patients affected by healthcare-associated infections. Limited treatment options challenge clinicians in both human and veterinary medicine. To summarize current evidence for the occurrence of antimicrobial-resistant bacteria and their zoonotic transmission between humans and animals with a focus on data from Germany. Review of scientific literature and publications from German national public health institutions. Methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β‑lactamase (ESBL) producing Enterobacteriaceae are frequently transmitted between animals and humans. The rates of asymptomatic carriage are increased among persons with livestock contact compared with the general population. The occurrence of carbapenemase-producing Enterobacteriaceae has been documented on German pig and chicken farms, but investigations into their prevalence and zoonotic importance are pending. Colistin is frequently used in veterinary medicine to treat diarrhoea and causes selection pressure for colistin-resistant Gram-negative bacteria harbouring mcr genes. Vancomycin-resistant enterococci (VRE), oxazolidinone-resistant Gram-positive bacteria and multiresistant staphylococci are further antimicrobial-resistant microorganisms, which might have a zoonotic potential. Besides human healthcare and livestock, the problem of antimicrobial-resistant bacteria also affects companion animals (e. g. dogs, cats and horses), wildlife and the environment, which underlines the need to prevent antimicrobial resistance in a One Health approach.
Sections du résumé
BACKGROUND
BACKGROUND
The increasing burden of antimicrobial-resistant bacteria causes morbidity and mortality, especially among patients affected by healthcare-associated infections. Limited treatment options challenge clinicians in both human and veterinary medicine.
OBJECTIVES
OBJECTIVE
To summarize current evidence for the occurrence of antimicrobial-resistant bacteria and their zoonotic transmission between humans and animals with a focus on data from Germany.
MATERIALS AND METHODS
METHODS
Review of scientific literature and publications from German national public health institutions.
RESULTS AND CONCLUSIONS
CONCLUSIONS
Methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum β‑lactamase (ESBL) producing Enterobacteriaceae are frequently transmitted between animals and humans. The rates of asymptomatic carriage are increased among persons with livestock contact compared with the general population. The occurrence of carbapenemase-producing Enterobacteriaceae has been documented on German pig and chicken farms, but investigations into their prevalence and zoonotic importance are pending. Colistin is frequently used in veterinary medicine to treat diarrhoea and causes selection pressure for colistin-resistant Gram-negative bacteria harbouring mcr genes. Vancomycin-resistant enterococci (VRE), oxazolidinone-resistant Gram-positive bacteria and multiresistant staphylococci are further antimicrobial-resistant microorganisms, which might have a zoonotic potential. Besides human healthcare and livestock, the problem of antimicrobial-resistant bacteria also affects companion animals (e. g. dogs, cats and horses), wildlife and the environment, which underlines the need to prevent antimicrobial resistance in a One Health approach.
Identifiants
pubmed: 30276566
doi: 10.1007/s00063-018-0487-x
pii: 10.1007/s00063-018-0487-x
doi:
Types de publication
Journal Article
Review
Langues
ger
Sous-ensembles de citation
IM
Pagination
189-197Références
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