Immunization of Mothers of Children with Cerebral Palsy in Rural Bangladesh.


Journal

Infectious disorders drug targets
ISSN: 2212-3989
Titre abrégé: Infect Disord Drug Targets
Pays: United Arab Emirates
ID NLM: 101269158

Informations de publication

Date de publication:
2020
Historique:
received: 18 08 2018
revised: 25 08 2018
accepted: 14 09 2018
pubmed: 3 10 2018
medline: 17 4 2021
entrez: 3 10 2018
Statut: ppublish

Résumé

Vaccination is one of the most effective public health tools for the prevention of infectious diseases, morbidity and disability. Little is known about the rate of maternal immunization among mothers of children with Cerebral Palsy (CP), as well as any possible role of maternal immunization in development of CP in the newborns. To determine the socio-demographic characteristics and self-reported vaccination status of mothers of children with CP and compare vaccination coverage in this cohort with national data on immunization. The study also aims to assess the vaccination status of children with CP. A subset of the Bangladesh CP Register (BCPR) cohort of women who had children with CP were recruited during April 2017 from a community based early intervention and rehabilitation program going on in Shahjadpur. Socio-demographic characteristics and maternal immunization status were assessed using a semi-structured questionnaire. The vaccination status of the children was also assessed by interviewing mother and observing the BCG marks. All data were compared with the corresponding information among general population using national vaccination coverage survey reports of the Ministry of Health and Family Welfare, Bangladesh. Sixty-eight mothers were interviewed of which 17.6% of mothers reported not receiving any vaccine during pregnancy. Tetanus vaccine was most commonly (82.0%) received during pregnancy. Overall coverage for at least two doses of tetanus toxoid (TT) among mothers of children with CP was significantly lower than the national tetanus coverage (79.4% versus 96.4%, p<0.01). Forty-two (61.7%) mothers with a child with CP reported having not received tetanus vaccine during their pregnancy compared to only twenty (29.4%) mothers with healthy children reported missing tetanus vaccination during their pregnancy. This difference was statistically significant (p<0.01). Hepatitis B and influenza vaccine were received by mothers of children with CP during the antenatal period (2 and 6 respectively). Immunization among mothers of children with CP is significantly poorer than the national coverage. Also, the immunization of the children with CP is poorer than the national EPI coverage. Our findings reflect the necessity for specific strategies to improve the vaccination coverage among mothers of children with disabilities especially CP and the children with CP.

Sections du résumé

BACKGROUND
Vaccination is one of the most effective public health tools for the prevention of infectious diseases, morbidity and disability. Little is known about the rate of maternal immunization among mothers of children with Cerebral Palsy (CP), as well as any possible role of maternal immunization in development of CP in the newborns.
OBJECTIVE
To determine the socio-demographic characteristics and self-reported vaccination status of mothers of children with CP and compare vaccination coverage in this cohort with national data on immunization. The study also aims to assess the vaccination status of children with CP.
METHODS
A subset of the Bangladesh CP Register (BCPR) cohort of women who had children with CP were recruited during April 2017 from a community based early intervention and rehabilitation program going on in Shahjadpur. Socio-demographic characteristics and maternal immunization status were assessed using a semi-structured questionnaire. The vaccination status of the children was also assessed by interviewing mother and observing the BCG marks. All data were compared with the corresponding information among general population using national vaccination coverage survey reports of the Ministry of Health and Family Welfare, Bangladesh.
RESULT
Sixty-eight mothers were interviewed of which 17.6% of mothers reported not receiving any vaccine during pregnancy. Tetanus vaccine was most commonly (82.0%) received during pregnancy. Overall coverage for at least two doses of tetanus toxoid (TT) among mothers of children with CP was significantly lower than the national tetanus coverage (79.4% versus 96.4%, p<0.01). Forty-two (61.7%) mothers with a child with CP reported having not received tetanus vaccine during their pregnancy compared to only twenty (29.4%) mothers with healthy children reported missing tetanus vaccination during their pregnancy. This difference was statistically significant (p<0.01). Hepatitis B and influenza vaccine were received by mothers of children with CP during the antenatal period (2 and 6 respectively).
CONCLUSION
Immunization among mothers of children with CP is significantly poorer than the national coverage. Also, the immunization of the children with CP is poorer than the national EPI coverage. Our findings reflect the necessity for specific strategies to improve the vaccination coverage among mothers of children with disabilities especially CP and the children with CP.

Identifiants

pubmed: 30277171
pii: IDDT-EPUB-93327
doi: 10.2174/1871526518666181001140817
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

303-308

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Arifuzzaman Khan (A)

Asian Institute of Disability and Development (AIDD), University of South Asia, Dhaka, Bangladesh

Fahim Ashher (F)

Asian Institute of Disability and Development (AIDD), University of South Asia, Dhaka, Bangladesh

Tasneem Karim (T)

Asian Institute of Disability and Development (AIDD), University of South Asia, Dhaka, Bangladesh
CSF Global, Dhaka, Bangladesh;
University of Sydney, Sydney, Australia

Aneeka Fatema (A)

University of Sydney, Sydney, Australia

Israt Jahan (I)

Asian Institute of Disability and Development (AIDD), University of South Asia, Dhaka, Bangladesh
CSF Global, Dhaka, Bangladesh;

Mohammad Muhit (M)

Asian Institute of Disability and Development (AIDD), University of South Asia, Dhaka, Bangladesh
CSF Global, Dhaka, Bangladesh;

Aditi Dey (A)

University of Sydney, Sydney, Australia
National Centre for Immunisation Research & Surveillance of Vaccine Preventable Diseases (NCIRS), Sydney, Australia

Frank Beard (F)

University of Sydney, Sydney, Australia
National Centre for Immunisation Research & Surveillance of Vaccine Preventable Diseases (NCIRS), Sydney, Australia

Gulam Khandaker (G)

Asian Institute of Disability and Development (AIDD), University of South Asia, Dhaka, Bangladesh
CSF Global, Dhaka, Bangladesh;
University of Sydney, Sydney, Australia

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