Engineering hydrogel viscoelasticity.

Elasticity Engineering Hydrogels Materials Testing Stress, Mechanical Viscosity
Agarose Damping component modulation Mechanobiology Polyacrylamide Viscoelasticity

Journal

Journal of the mechanical behavior of biomedical materials
ISSN: 1878-0180
Titre abrégé: J Mech Behav Biomed Mater
Pays: Netherlands
ID NLM: 101322406

Informations de publication

Date de publication:
01 2019
Historique:
received: 10 05 2018
revised: 14 09 2018
accepted: 20 09 2018
pubmed: 5 10 2018
medline: 12 2 2020
entrez: 5 10 2018
Statut: ppublish

Résumé

The aim of this study was to identify a method for modifying the time-dependent viscoelastic properties of gels without altering the elastic component. To this end, two hydrogels commonly used in biomedical applications, agarose and acrylamide, were prepared in aqueous solutions of dextran with increasing concentrations (0%, 2% and 5% w/v) and hence increasing viscosities. Commercial polyurethane sponges soaked in the same solutions were used as controls, since, unlike in hydrogels, the liquid in these sponge systems is poorly bound to the polymer network. Sample viscoelastic properties were characterised using the epsilon-dot method, based on compression tests at different constant strain-rates. Experimental data were fitted to a standard linear solid model. While increasing the liquid viscosity in the controls resulted in a significant increase of the characteristic relaxation time (τ), both the instantaneous (E

Identifiants

DOI: 10.1016/j.jmbbm.2018.09.031 PMID: 30286375
pubmed: 30286375
pii: S1751-6161(18)30725-2
doi: 10.1016/j.jmbbm.2018.09.031
pii:
doi:

Substances chimiques

Hydrogels 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

162-167

Informations de copyright

Copyright © 2018 Elsevier Ltd. All rights reserved.

Auteurs

Ludovica Cacopardo (L)

Research Centre "E. Piaggio", University of Pisa, Largo Lucio Lazzarino 1, 56122 Pisa, Italy; Department of Information Engineering, University of Pisa, Via Girolamo Caruso 16, 56122 Pisa, Italy.

Nicole Guazzelli (N)

Research Centre "E. Piaggio", University of Pisa, Largo Lucio Lazzarino 1, 56122 Pisa, Italy.

Roberta Nossa (R)

Research Centre "E. Piaggio", University of Pisa, Largo Lucio Lazzarino 1, 56122 Pisa, Italy; Department of Information Engineering, University of Pisa, Via Girolamo Caruso 16, 56122 Pisa, Italy.

Giorgio Mattei (G)

Department of Information Engineering, University of Pisa, Via Girolamo Caruso 16, 56122 Pisa, Italy; Optics11 B.V., De Boelelaan 1081, 1081 HV Amsterdam, the Netherlands; Biophotonics & Medical Imaging and LaserLaB, VU University Amsterdam, De Boelelaan 1105, 1081 HV Amsterdam, the Netherlands.

Arti Ahluwalia (A)

Research Centre "E. Piaggio", University of Pisa, Largo Lucio Lazzarino 1, 56122 Pisa, Italy; Department of Information Engineering, University of Pisa, Via Girolamo Caruso 16, 56122 Pisa, Italy. Electronic address: arti.ahluwalia@unipi.it.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiques › Phénomènes mécaniques › Élasticité › Engineering hydrogel viscoelasticity.
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Engineering hydrogel viscoelasticity.
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Engineering hydrogel viscoelasticity.
questionsmedicales.fr › Techniques d'investigation › Test de matériaux › Engineering hydrogel viscoelasticity.
questionsmedicales.fr › Phénomènes physiques › Phénomènes mécaniques › Contrainte mécanique › Engineering hydrogel viscoelasticity.
questionsmedicales.fr › Phénomènes chimiques › Viscosité › Engineering hydrogel viscoelasticity.