Validation of Quantitative Microbial Risk Assessment Using Epidemiological Data from Outbreaks of Waterborne Gastrointestinal Disease.
Algorithms
Caliciviridae Infections
/ epidemiology
Cryptosporidiosis
/ epidemiology
Cryptosporidium
Disease Outbreaks
Drinking Water
Environmental Monitoring
Gastrointestinal Diseases
/ epidemiology
Giardia
Giardiasis
/ epidemiology
Health Policy
Humans
Norovirus
Public Health
Reproducibility of Results
Risk Assessment
/ methods
Water Microbiology
Epidemiology
outbreaks
quantitative microbial risk assessment
validation
water
Journal
Risk analysis : an official publication of the Society for Risk Analysis
ISSN: 1539-6924
Titre abrégé: Risk Anal
Pays: United States
ID NLM: 8109978
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
28
09
2017
revised:
06
08
2018
accepted:
20
08
2018
pubmed:
5
10
2018
medline:
7
5
2019
entrez:
5
10
2018
Statut:
ppublish
Résumé
The assumptions underlying quantitative microbial risk assessment (QMRA) are simple and biologically plausible, but QMRA predictions have never been validated for many pathogens. The objective of this study was to validate QMRA predictions against epidemiological measurements from outbreaks of waterborne gastrointestinal disease. I screened 2,000 papers and identified 12 outbreaks with the necessary data: disease rates measured using epidemiological methods and pathogen concentrations measured in the source water. Eight of the 12 outbreaks were caused by Cryptosporidium, three by Giardia, and one by norovirus. Disease rates varied from 5.5 × 10
Substances chimiques
Drinking Water
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
599-615Subventions
Organisme : Agricultural Research Service
ID : CRIS Project No. 5090-12630-005-00D
Pays : International
Informations de copyright
Published 2018. This article is a U.S. government work and is in the public domain in the USA.