Rapid, Quantitative, and Ultrasensitive Point-of-Care Testing: A Portable SERS Reader for Lateral Flow Assays in Clinical Chemistry.

Raman spectroscopy hCG pregnancy test lateral flow assay point-of-care testing portable SERS reader

Journal

Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543

Informations de publication

Date de publication:
08 01 2019
Historique:
received: 21 09 2018
pubmed: 6 10 2018
medline: 1 8 2020
entrez: 6 10 2018
Statut: ppublish

Résumé

The design of a portable Raman/SERS-LFA reader with line illumination using a custom-made fiber optic probe for rapid, quantitative, and ultrasensitive point-of-care testing (POCT) is presented. The pregnancy hormone human chorionic gonadotropin (hCG) is detectable in clinical samples within only 2-5 s down to approximately 1.6 mIU mL

Identifiants

pubmed: 30288886
doi: 10.1002/anie.201810917
pmc: PMC6582447
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

442-446

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : WA 3369/1-1
Pays : International

Informations de copyright

© 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

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Auteurs

Vi Tran (V)

Department of Chemistry, Center for Nanointegration Duisburg-Essen (CENIDE), and, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstraße 5, 45141, Essen, Germany.

Bernd Walkenfort (B)

Department of Chemistry, Center for Nanointegration Duisburg-Essen (CENIDE), and, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstraße 5, 45141, Essen, Germany.

Matthias König (M)

Department of Chemistry, Center for Nanointegration Duisburg-Essen (CENIDE), and, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstraße 5, 45141, Essen, Germany.

Mohammad Salehi (M)

Department of Chemistry, Center for Nanointegration Duisburg-Essen (CENIDE), and, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstraße 5, 45141, Essen, Germany.

Sebastian Schlücker (S)

Department of Chemistry, Center for Nanointegration Duisburg-Essen (CENIDE), and, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Universitätsstraße 5, 45141, Essen, Germany.

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