DOCUMENTATION OF A NEW CHOROIDAL NEVUS.
Aged
Angiogenesis Inhibitors
/ therapeutic use
Choroid Neoplasms
/ diagnosis
Documentation
Fluorescein Angiography
Follow-Up Studies
Humans
Male
Multimodal Imaging
Nevus, Pigmented
/ diagnosis
Ophthalmoscopy
Receptors, Vascular Endothelial Growth Factor
/ therapeutic use
Recombinant Fusion Proteins
/ therapeutic use
Tomography, Optical Coherence
Visual Acuity
Journal
Retinal cases & brief reports
ISSN: 1937-1578
Titre abrégé: Retin Cases Brief Rep
Pays: United States
ID NLM: 101298744
Informations de publication
Date de publication:
01 May 2021
01 May 2021
Historique:
pubmed:
6
10
2018
medline:
30
10
2021
entrez:
6
10
2018
Statut:
ppublish
Résumé
To describe the occurrence of an acquired choroidal nevus in a 73-year-old white man. Case report. A 73-year-old white man was referred for an evaluation and treatment of macular changes in his left eye consistent with pachychoroid neovasculopathy. Baseline funduscopic examination and color fundus photographs showed two small peripheral choroidal nevi in the right eye and a single small choroidal nevus in the far temporal macula of the left eye. Treatment with intravitreal aflibercept was initiated in the left eye on a treat-and-extend dosing regimen. Approximately 1 year later, a new pigmented choroidal lesion was detected in the left macula in an area where previous high-resolution color fundus photographs had shown no abnormal pigmentation. Swept-source optical coherence tomography of the new pigmented lesion showed flat hyperreflectivity within the inner choroid consistent with a small choroidal nevus. The patient was referred to his internist who found no evidence of an occult malignancy. Over the course of more than 4 additional years of continuous follow-up, the new choroidal nevus remained stable, no new fundus abnormalities were detected in either eye, and the patient remained medically stable. To the best of our knowledge, this is the first documented case of a new choroidal nevus. Multimodal imaging performed before lesion detection and over the ensuing 4 years showed its stability, thus allowing for the conclusion that it was a benign choroidal nevus rather than a neoplastic or paraneoplastic process.
Identifiants
pubmed: 30289791
pii: 01271216-202105000-00003
doi: 10.1097/ICB.0000000000000822
doi:
Substances chimiques
Angiogenesis Inhibitors
0
Recombinant Fusion Proteins
0
aflibercept
15C2VL427D
Receptors, Vascular Endothelial Growth Factor
EC 2.7.10.1
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
202-206Références
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