Effect of zinc oxide sources and dosages on gut microbiota and integrity of weaned piglets.
Escherichia coli
intestinal alkaline phosphatase
tight junctions
transepithelial electrical resistance
zinc solubility
Journal
Journal of animal physiology and animal nutrition
ISSN: 1439-0396
Titre abrégé: J Anim Physiol Anim Nutr (Berl)
Pays: Germany
ID NLM: 101126979
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
25
02
2018
revised:
01
09
2018
accepted:
03
09
2018
pubmed:
10
10
2018
medline:
17
4
2019
entrez:
10
10
2018
Statut:
ppublish
Résumé
Zinc oxide (ZnO) supplied at pharmacological dosage in diets of weaned piglets improves growth performance. However, it causes environmental contamination and induces bacterial antibiotic resistance, yet this practice is debated. The effects on gut microbiota and integrity in weaned piglets of conventional ZnO at nutritional and pharmacological dosage (110 and 2,400 mg/kg Zn, respectively) were compared to an alternative ZnO source at 110 and 220 mg/kg Zn. Each of the four treatments was applied to four pens (two piglets/pen; weaning age, 20 days) for 15 days, and piglets were sampled on day 15 to determine indices of gut integrity. Feeding conventional ZnO at 2,400 mg/kg Zn reduced coliforms and Escherichia coli in distal small intestine as compared to conventional ZnO at 110 mg/kg (-1.7 and -1.4 log
Substances chimiques
Alkaline Phosphatase
EC 3.1.3.1
Zinc
J41CSQ7QDS
Zinc Oxide
SOI2LOH54Z
Types de publication
Clinical Trial, Veterinary
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
231-241Subventions
Organisme : Animine
Informations de copyright
© 2018 Blackwell Verlag GmbH.