Expression of AR-V7 and ARv


Journal

Clinical cancer research : an official journal of the American Association for Cancer Research
ISSN: 1557-3265
Titre abrégé: Clin Cancer Res
Pays: United States
ID NLM: 9502500

Informations de publication

Date de publication:
15 03 2019
Historique:
received: 26 01 2018
revised: 11 05 2018
accepted: 03 10 2018
pubmed: 12 10 2018
medline: 28 5 2020
entrez: 11 10 2018
Statut: ppublish

Résumé

Biomarkers aiding treatment optimization in metastatic castration-resistant prostate cancer (mCRPC) are scarce. The presence or absence of androgen receptor (AR) splice variants, AR-V7 and AR Of the 54 evaluable patients, 36 (67%) were AR-V7 Although detection of both CTC-specific AR-V7 and AR

Identifiants

pubmed: 30301829
pii: 1078-0432.CCR-18-0320
doi: 10.1158/1078-0432.CCR-18-0320
pmc: PMC6432911
mid: NIHMS1509272
doi:

Substances chimiques

AR protein, human 0
Biomarkers, Tumor 0
Protein Isoforms 0
Receptors, Androgen 0
Taxoids 0
Docetaxel 15H5577CQD
cabazitaxel 51F690397J
KLK3 protein, human EC 3.4.21.-
Kallikreins EC 3.4.21.-
Prostate-Specific Antigen EC 3.4.21.77
Prednisone VB0R961HZT

Banques de données

ClinicalTrials.gov
['NCT01718353']

Types de publication

Clinical Trial, Phase II Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1880-1888

Subventions

Organisme : NCI NIH HHS
ID : R21 CA216800
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA062948
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA203702
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002384
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn

Informations de copyright

©2018 American Association for Cancer Research.

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Auteurs

Scott T Tagawa (ST)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York. pag2015@med.cornell.edu stt2007@med.cornell.edu.

Emmanuel S Antonarakis (ES)

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

Ada Gjyrezi (A)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Giuseppe Galletti (G)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Seaho Kim (S)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Daniel Worroll (D)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

John Stewart (J)

Sanofi, Laval, Quebec, Canada.

Atef Zaher (A)

Sanofi, Laval, Quebec, Canada.

Ted P Szatrowski (TP)

Sanofi, Bridgewater, New Jersey.

Karla V Ballman (KV)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Katsuhiro Kita (K)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Shinsuke Tasaki (S)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Yang Bai (Y)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Luigi Portella (L)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Brian J Kirby (BJ)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.
Cornell University, Ithaca, New York.

Fred Saad (F)

University of Montreal Hospital Center, Montreal, Quebec, Canada.

Mario A Eisenberger (MA)

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

David M Nanus (DM)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York.

Paraskevi Giannakakou (P)

Weill Cornell Medicine/Meyer Cancer Center, New York, New York. pag2015@med.cornell.edu stt2007@med.cornell.edu.

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Classifications MeSH