Management of acute liver failure. Clinical guideline from the Catalan Society of Digestology.

Manejo de la insuficiencia hepática aguda grave. Documento de posicionamiento de la Societat Catalana de Digestologia.
Acute liver failure Artificial liver support Insuficiencia hepática aguda grave Intensive care unit Liver transplantation Soporte hepático artificial Trasplante hepático Unidad de cuidados intensivos

Journal

Gastroenterologia y hepatologia
ISSN: 0210-5705
Titre abrégé: Gastroenterol Hepatol
Pays: Spain
ID NLM: 8406671

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 22 06 2018
revised: 19 07 2018
accepted: 27 07 2018
pubmed: 13 10 2018
medline: 2 8 2019
entrez: 13 10 2018
Statut: ppublish

Résumé

Acute liver failure is an uncommon and severe disease characterised by a rapid onset of severe hepatocellular failure in individuals without previous liver disease. Initial management of this entity determines the outcome of the patient. Initial contact with the acute liver failure patients usually occurs in the emergency department, digestology clinic or, in more severe cases, intensive care units. The management of acute liver failure patients in all these cases must be multidisciplinary, involving surgeons and hepatologists who are experts in this condition, meaning those from hospitals with active liver transplant programmes. This article reviews the current body of evidence concerning the medical management of acute liver failure patients, from the suspected diagnosis and initial management to intensive medical treatment, including the need for an emergency liver transplantation. Moreover, we also review the use of artificial liver support systems in this setting.

Identifiants

pubmed: 30309739
pii: S0210-5705(18)30242-5
doi: 10.1016/j.gastrohep.2018.07.013
pii:
doi:

Types de publication

Journal Article Practice Guideline Review

Langues

eng spa

Pagination

51-64

Informations de copyright

Copyright © 2018 Elsevier España, S.L.U. All rights reserved.

Auteurs

Àngels Escorsell (À)

UCI-IMDM, Servei d'Hepatologia, Hospital Clínic, Barcelona, España; IDIBAPS, Universitat de Barcelona, Barcelona, España; CIBERehd, Instituto de Salud Carlos III, Madrid, España. Electronic address: aescor@clinic.cat.

José Castellote (J)

IDIBAPS, Universitat de Barcelona, Barcelona, España; CIBERehd, Instituto de Salud Carlos III, Madrid, España; Hepatologia i Unitat de Trasplantament Hepàtic, Servei d'Aparell Digestiu, Hospital Universitari de Bellvitge, l'Hospitalet del Llobregat, España.

Jordi Sánchez-Delgado (J)

CIBERehd, Instituto de Salud Carlos III, Madrid, España; Servei d'Aparell Digestiu, Unitat d'Hepatologia. Hospital Parc Taulí, Institut d'Investigació i Innovació Parc Taulí I3PT, Sabadell, España; Universitat Autònoma de Barcelona, Cerdanyola, España.

Ramon Charco (R)

CIBERehd, Instituto de Salud Carlos III, Madrid, España; Universitat Autònoma de Barcelona, Cerdanyola, España; Servei de Cirurgia General, Hospital de la Vall d'Hebrón, Barcelona, España.

Gonzalo Crespo (G)

IDIBAPS, Universitat de Barcelona, Barcelona, España; CIBERehd, Instituto de Salud Carlos III, Madrid, España; Secció de Trasplantament Hepàtic, Servei d'Hepatologia, Hospital Clínic, Barcelona, España.

Javier Fernández (J)

UCI-IMDM, Servei d'Hepatologia, Hospital Clínic, Barcelona, España; IDIBAPS, Universitat de Barcelona, Barcelona, España; CIBERehd, Instituto de Salud Carlos III, Madrid, España; European Foundation for the Study of Chronic Liver Failure; EF CLIF, Barcelona, España.

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Classifications MeSH