Gestational diabetes mellitus in a multiethnic population in Spain: Incidence and factors associated to impaired glucose tolerance one year after delivery.
Incidencia y factores asociados al metabolismo alterado de la glucosa un año después del parto en una población multiétnica de mujeres con diabetes mellitus gestacional en España.
Adult
Asia
/ ethnology
Diabetes Mellitus, Type 2
/ ethnology
Diabetes, Gestational
/ ethnology
Ethnicity
/ statistics & numerical data
Female
Follow-Up Studies
Glucose Intolerance
/ ethnology
Humans
Incidence
Morocco
/ ethnology
Observational Studies as Topic
/ statistics & numerical data
Pregnancy
Retrospective Studies
Spain
/ epidemiology
Diabetes mellitus gestacional
Diabetes mellitus tipo 2
Gestational diabetes mellitus
Glucose intolerance
Intolerancia a la glucosa
Prediabetes
Type 2 diabetes mellitus
Journal
Endocrinologia, diabetes y nutricion
ISSN: 2530-0180
Titre abrégé: Endocrinol Diabetes Nutr (Engl Ed)
Pays: Spain
ID NLM: 101717565
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
13
04
2018
revised:
23
07
2018
accepted:
30
07
2018
pubmed:
13
10
2018
medline:
7
1
2020
entrez:
13
10
2018
Statut:
ppublish
Résumé
Women with history of gestational diabetes mellitus (GDM) are at increased risk for diabetes. Ethnicity may modify such risk, but no studies have been conducted in our environment. The aim of this study was to assess the incidence of type 2 diabetes mellitus and prediabetes one year after delivery in women with GDM and in a multiethnic background and to identify the associated factors. A retrospective analysis of a prospective, observational cohort of women with GDM who attended annual postpartum follow-up visits at Hospital del Mar from January 2004 to March 2016. Three hundred and five women attended postpartum follow-up visits. Of these, 47.2% were Caucasian, 22% from South-Central Asia, 12% from Latin America, and 10% from Morocco and East Asia. Incidence rates of type 2 diabetes mellitus and prediabetes in these patients were 5.2 and 36.6%, respectively. In a multivariate analysis, non-Caucasian origin (OR=3.15, 95% CI [1.85-5.39]), recurrent gestational diabetes (OR=2.26, 95% CI [1.11-4.59]), and pre-pregnancy body mass index (OR=1.09, 95% CI [1.04-1.15]) were independent predictors of impaired glucose tolerance. In a multiethnic Spanish population of women with GDM, incidence of impaired glucose tolerance in the first year after delivery was 41.8%, with a three-fold increased risk for women of non-Caucasian ethnicity.
Sections du résumé
BACKGROUND AND AIM
OBJECTIVE
Women with history of gestational diabetes mellitus (GDM) are at increased risk for diabetes. Ethnicity may modify such risk, but no studies have been conducted in our environment. The aim of this study was to assess the incidence of type 2 diabetes mellitus and prediabetes one year after delivery in women with GDM and in a multiethnic background and to identify the associated factors.
PATIENTS AND METHODS
METHODS
A retrospective analysis of a prospective, observational cohort of women with GDM who attended annual postpartum follow-up visits at Hospital del Mar from January 2004 to March 2016.
RESULTS
RESULTS
Three hundred and five women attended postpartum follow-up visits. Of these, 47.2% were Caucasian, 22% from South-Central Asia, 12% from Latin America, and 10% from Morocco and East Asia. Incidence rates of type 2 diabetes mellitus and prediabetes in these patients were 5.2 and 36.6%, respectively. In a multivariate analysis, non-Caucasian origin (OR=3.15, 95% CI [1.85-5.39]), recurrent gestational diabetes (OR=2.26, 95% CI [1.11-4.59]), and pre-pregnancy body mass index (OR=1.09, 95% CI [1.04-1.15]) were independent predictors of impaired glucose tolerance.
CONCLUSIONS
CONCLUSIONS
In a multiethnic Spanish population of women with GDM, incidence of impaired glucose tolerance in the first year after delivery was 41.8%, with a three-fold increased risk for women of non-Caucasian ethnicity.
Identifiants
pubmed: 30309812
pii: S2530-0164(18)30191-5
doi: 10.1016/j.endinu.2018.07.007
pii:
doi:
Types de publication
Journal Article
Langues
eng
spa
Sous-ensembles de citation
IM
Pagination
240-246Informations de copyright
Copyright © 2018. Publicado por Elsevier España, S.L.U.