Interventions to improve retention-in-care and treatment adherence among patients with drug-resistant tuberculosis: a systematic review.


Journal

The European respiratory journal
ISSN: 1399-3003
Titre abrégé: Eur Respir J
Pays: England
ID NLM: 8803460

Informations de publication

Date de publication:
01 2019
Historique:
received: 01 06 2018
accepted: 20 09 2018
pubmed: 13 10 2018
medline: 2 10 2020
entrez: 13 10 2018
Statut: epublish

Résumé

The global loss to follow-up (LTFU) rate among drug-resistant tuberculosis (DR-TB) patients remains high at 15%. We conducted a systematic review to explore interventions to reduce LTFU during DR-TB treatment.We searched for studies published between January 2000 and December 2017 that provided any form of psychosocial or material support for patients with DR-TB. We estimated point estimates and 95% confidence intervals of the proportion LTFU. We performed subgroup analyses and pooled estimates using an exact binomial likelihood approach.We included 35 DR-TB cohorts from 25 studies, with a pooled proportion LTFU of 17 (12-23)%. Cohorts that received any form of psychosocial or material support had lower LTFU rates than those that received standard care. Psychosocial support throughout treatment,

Identifiants

pubmed: 30309972
pii: 13993003.01030-2018
doi: 10.1183/13993003.01030-2018
pii:
doi:

Substances chimiques

Antitubercular Agents 0

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAID NIH HHS
ID : K23 AI098479
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright ©ERS 2019.

Déclaration de conflit d'intérêts

Conflict of interest: S. Law has nothing to disclose. Conflict of interest: A. Daftary has nothing to disclose. Conflict of interest: M. O'Donnell has nothing to disclose. Conflict of interest: N. Padayatchi has nothing to disclose. Conflict of interest: L. Calzavara has nothing to disclose. Conflict of interest: D. Menzies has nothing to disclose.

Auteurs

Stephanie Law (S)

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.

Amrita Daftary (A)

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.
McGill International TB Centre, McGill University, Montreal, QC, Canada.
CAPRISA-MRC TB-HIV Pathogenesis and Treatment Unit, Durban, South Africa.

Max O'Donnell (M)

CAPRISA-MRC TB-HIV Pathogenesis and Treatment Unit, Durban, South Africa.
Division of Pulmonary, Allergy and Critical Care Medicine, and Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY, USA.

Nesri Padayatchi (N)

CAPRISA-MRC TB-HIV Pathogenesis and Treatment Unit, Durban, South Africa.

Liviana Calzavara (L)

Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

Dick Menzies (D)

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.
McGill International TB Centre, McGill University, Montreal, QC, Canada.

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