The role of emergency laparoscopic colectomy for complicated sigmoid diverticulits: A systematic review and meta-analysis.

Acute care surgery Acute complicated diverticulitis Colorectal emergency surgery Diverticulitis Emergency sigmoid resection Hartmann's procedure Laparoscopic sigmoidectomy Sigmoidectomy

Journal

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
ISSN: 1479-666X
Titre abrégé: Surgeon
Pays: Scotland
ID NLM: 101168329

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 10 06 2018
accepted: 21 08 2018
pubmed: 14 10 2018
medline: 16 5 2020
entrez: 14 10 2018
Statut: ppublish

Résumé

Nowadays sigmoidectomy is recommended as "gold standard" treatment for generalized purulent or faecal peritonitis from sigmoid perforated diverticulitis. This systematic review and meta-analysis aimed to assess effectiveness and safety of laparoscopic access versus open sigmoidectomy in acute setting. A systematic literature search was performed for randomized controlled trials (RCTs) and non-RCTs published in PubMed, SCOPUS and Web of Science. The search yielded four non-RCTs encompassing 436 patients undergoing either laparoscopic (181 patients, 41.51%) versus open sigmoid resection (255 patients, 58.49%). All studies reported ASA scores, but only four studies reported other severity scoring systems (Mannheim Peritonitis Index, P-POSSUM). Level of surgical expertise was reported in only one study. Laparoscopy improves slightly the rates of overall post-operative complications and post-operative hospital stay, respectively (RR 0.62, 95% CI 0.49 to 0.80 and MD -6.53, 95% CI -16.05 to 2.99). Laparoscopy did not seem to improve the other clinical outcomes: rate of Hartmann's vs anastomosis, operating time, reoperation rate and postoperative 30-day mortality. In this review four prospective studies were included, over 20 + year period, including overall 400 + patients. This meta-analysis revealed significant advantages associated with a laparoscopic over open approach to emergency sigmoidectomy in acute diverticulitis in terms of postoperative complication rates, although no differences were found in other outcomes. The lack of hemodynamic data and reasons for operative approach hamper interpretation of the data suggesting that patients undergoing open surgery were sicker and these results must be considered with extreme caution and this hypothesis requires confirmation by future prospective randomised controlled trials.

Sections du résumé

BACKGROUND BACKGROUND
Nowadays sigmoidectomy is recommended as "gold standard" treatment for generalized purulent or faecal peritonitis from sigmoid perforated diverticulitis. This systematic review and meta-analysis aimed to assess effectiveness and safety of laparoscopic access versus open sigmoidectomy in acute setting.
METHODS METHODS
A systematic literature search was performed for randomized controlled trials (RCTs) and non-RCTs published in PubMed, SCOPUS and Web of Science.
RESULTS RESULTS
The search yielded four non-RCTs encompassing 436 patients undergoing either laparoscopic (181 patients, 41.51%) versus open sigmoid resection (255 patients, 58.49%). All studies reported ASA scores, but only four studies reported other severity scoring systems (Mannheim Peritonitis Index, P-POSSUM). Level of surgical expertise was reported in only one study. Laparoscopy improves slightly the rates of overall post-operative complications and post-operative hospital stay, respectively (RR 0.62, 95% CI 0.49 to 0.80 and MD -6.53, 95% CI -16.05 to 2.99). Laparoscopy did not seem to improve the other clinical outcomes: rate of Hartmann's vs anastomosis, operating time, reoperation rate and postoperative 30-day mortality.
CONCLUSION CONCLUSIONS
In this review four prospective studies were included, over 20 + year period, including overall 400 + patients. This meta-analysis revealed significant advantages associated with a laparoscopic over open approach to emergency sigmoidectomy in acute diverticulitis in terms of postoperative complication rates, although no differences were found in other outcomes. The lack of hemodynamic data and reasons for operative approach hamper interpretation of the data suggesting that patients undergoing open surgery were sicker and these results must be considered with extreme caution and this hypothesis requires confirmation by future prospective randomised controlled trials.

Identifiants

pubmed: 30314956
pii: S1479-666X(18)30115-X
doi: 10.1016/j.surge.2018.08.010
pii:
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

360-369

Informations de copyright

Copyright © 2018 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

Auteurs

Roberto Cirocchi (R)

Department of Surgical and Biomedical Sciences, University of Perugia, Italy. Electronic address: roberto.cirocchi@unipg.it.

Nicola Fearnhead (N)

Cambridge Colorectal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. Electronic address: nicola.fearnhead@cambridgecolorectal.org.

Nereo Vettoretto (N)

Montichiari Surgery, ASST Spedali Civili, Brescia, Italy. Electronic address: nereovet@gmail.com.

Diletta Cassini (D)

Policlinic of Abano Terme, Padua, Italy. Electronic address: diletta_cassini@yahoo.it.

Georgi Popivanov (G)

Military Medical Academy, Clinic of Endoscopic, Endocrine Surgery and Coloproctology, Sofia, Bulgaria. Electronic address: gerasimpopivanov@rocketmail.com.

Brandon Michael Henry (BM)

Department of Anatomy, Jagiellonian University Medical College, Krakow, Poland. Electronic address: bmhenry55@gmail.com.

Krzysztof Tomaszewski (K)

Department of Anatomy, Jagiellonian University Medical College, Krakow, Poland. Electronic address: krtomaszewski@gmail.com.

Vito D'Andrea (V)

Department of Surgical Sciences, The University of Rome "La Sapienza", Rome, Italy. Electronic address: vito.dandrea@uniroma1.it.

Justin Davies (J)

Cambridge Colorectal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. Electronic address: justin.davies@addenbrookes.nhs.uk.

Salomone Di Saverio (S)

Cambridge Colorectal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. Electronic address: salomone.disaverio@addenbrookes.nhs.uk.

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Classifications MeSH