Twelve-month outcomes of Eustachian tube procedures for management of patulous Eustachian tube dysfunction.
Adolescent
Adult
Aged
Aged, 80 and over
Botulinum Toxins
/ administration & dosage
Child
Ear Diseases
/ diagnosis
Eustachian Tube
/ surgery
Female
Humans
Male
Middle Aged
Middle Ear Ventilation
Natural Orifice Endoscopic Surgery
Otologic Surgical Procedures
Retrospective Studies
Treatment Outcome
Young Adult
Eustachian tube
Patulous Eustachian tube
autophony
Journal
The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
30
03
2018
revised:
15
06
2018
accepted:
20
06
2018
pubmed:
17
10
2018
medline:
18
5
2019
entrez:
17
10
2018
Statut:
ppublish
Résumé
To determine the 12-month effectiveness of transnasal-transoral endoscopic surgical procedures for eliminating symptoms of patulous Eustachian tube dysfunction (PETD). Retrospective chart review METHODS: Patients with medically refractory PETD underwent one of the following procedures: 1) shim (catheter) insertion, 2) calcium hydroxyapatite injection, 3) patulous Eustachian tube (ET) reconstruction, or 4) obliteration of the ET lumen. Time to recurrence of any PETD symptoms was recorded, and success was determined as complete symptom resolution at 12 months. The frailty model, an extension of the Cox proportional hazards model, was used for the survival analysis. A total of 241 procedures were performed in 80 patients. Median duration of symptom relief after surgery was 5.0 months (interquartile range [IQR]: 1.1-15.5 months) and varied by procedure type, ranging from 3.0 months (IQR: 0.7-7.0 months) for calcium hydroxyapatite injection to 20.6 months (3.4-35.9 months) for obliteration. Compared to shim insertion, the risk of 12-month failure was significantly higher for calcium hydroxyapatite injection (hazard ratio [HR] = 2.18; 95% confidence interval [CI] 1.29, 3.67; P = 0.004) and patulous ET reconstruction (HR = 1.62; 95% CI 1.04, 2.52; P = 0.035). Patients undergoing shim insertion (52.2%) and obliteration (81.8%) were likely to require pressure equalization tubes or to have had otitis media with effusion. Although all procedures potentially resulted in symptom resolution, placement of a shim or obliteration of the ET lumen was more likely to achieve 12-month resolution of PETD symptoms and more likely to result in otitis media with effusion than hydroxyapatite injection or patulous ET reconstruction. Level 4 Laryngoscope, 129:222-228, 2019.
Substances chimiques
Botulinum Toxins
EC 3.4.24.69
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
222-228Informations de copyright
© 2018 The American Laryngological, Rhinological and Otological Society, Inc.