Twelve-month outcomes of Eustachian tube procedures for management of patulous Eustachian tube dysfunction.


Journal

The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378

Informations de publication

Date de publication:
01 2019
Historique:
received: 30 03 2018
revised: 15 06 2018
accepted: 20 06 2018
pubmed: 17 10 2018
medline: 18 5 2019
entrez: 17 10 2018
Statut: ppublish

Résumé

To determine the 12-month effectiveness of transnasal-transoral endoscopic surgical procedures for eliminating symptoms of patulous Eustachian tube dysfunction (PETD). Retrospective chart review METHODS: Patients with medically refractory PETD underwent one of the following procedures: 1) shim (catheter) insertion, 2) calcium hydroxyapatite injection, 3) patulous Eustachian tube (ET) reconstruction, or 4) obliteration of the ET lumen. Time to recurrence of any PETD symptoms was recorded, and success was determined as complete symptom resolution at 12 months. The frailty model, an extension of the Cox proportional hazards model, was used for the survival analysis. A total of 241 procedures were performed in 80 patients. Median duration of symptom relief after surgery was 5.0 months (interquartile range [IQR]: 1.1-15.5 months) and varied by procedure type, ranging from 3.0 months (IQR: 0.7-7.0 months) for calcium hydroxyapatite injection to 20.6 months (3.4-35.9 months) for obliteration. Compared to shim insertion, the risk of 12-month failure was significantly higher for calcium hydroxyapatite injection (hazard ratio [HR] = 2.18; 95% confidence interval [CI] 1.29, 3.67; P = 0.004) and patulous ET reconstruction (HR = 1.62; 95% CI 1.04, 2.52; P = 0.035). Patients undergoing shim insertion (52.2%) and obliteration (81.8%) were likely to require pressure equalization tubes or to have had otitis media with effusion. Although all procedures potentially resulted in symptom resolution, placement of a shim or obliteration of the ET lumen was more likely to achieve 12-month resolution of PETD symptoms and more likely to result in otitis media with effusion than hydroxyapatite injection or patulous ET reconstruction. Level 4 Laryngoscope, 129:222-228, 2019.

Identifiants

pubmed: 30325505
doi: 10.1002/lary.27443
doi:

Substances chimiques

Botulinum Toxins EC 3.4.24.69

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

222-228

Informations de copyright

© 2018 The American Laryngological, Rhinological and Otological Society, Inc.

Auteurs

Bryan K Ward (BK)

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.

Wei-Chieh Chao (WC)

Department of Otolaryngology, Chang Gung Memorial Hospital, Keelong, Chang Gung University, Taoyuan, Taiwan.

Godwin Abiola (G)

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.

Kosuke Kawai (K)

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, U.S.A.

Yehia Ashry (Y)

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, U.S.A.

Tali Rasooly (T)

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, U.S.A.

Dennis S Poe (DS)

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.

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Classifications MeSH