Endovascular Stroke Therapy with a Novel 6-French Aspiration Catheter.


Journal

Cardiovascular and interventional radiology
ISSN: 1432-086X
Titre abrégé: Cardiovasc Intervent Radiol
Pays: United States
ID NLM: 8003538

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 18 07 2018
accepted: 10 10 2018
pubmed: 18 10 2018
medline: 9 2 2019
entrez: 18 10 2018
Statut: ppublish

Résumé

Direct thrombus aspiration is increasingly used as a first-line therapy in acute ischemic stroke with large vessel occlusion. We assessed the performance and safety of a novel aspiration catheter available: the 6-French AXS Catalyst catheter. We conducted a cohort study from a prospective clinical registry of consecutive stroke patients treated by mechanical thrombectomy between March 2016 and July 2016. Baseline clinical and imaging characteristics, recanalization rates, complications, and clinical outcomes were analyzed. Among the 60 patients included, 30 were treated using aspiration alone, 14 were treated using aspiration and then stent retriever as a rescue therapy, and 16 were treated using aspiration combined with a stent retriever straightaway. Successful recanalization (mTICI2b/3) was achieved in 85% patients and functional independence in 48.3%. We observed one intracranial perforation and one vertebral artery dissection. Symptomatic intracranial hemorrhage occurred in 5% and mortality in 21.7%. Endovascular stroke therapy using the AXS Catalyst catheter seems safe and effective, with similar performance than other reperfusion catheters.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
Direct thrombus aspiration is increasingly used as a first-line therapy in acute ischemic stroke with large vessel occlusion. We assessed the performance and safety of a novel aspiration catheter available: the 6-French AXS Catalyst catheter.
MATERIALS AND METHODS METHODS
We conducted a cohort study from a prospective clinical registry of consecutive stroke patients treated by mechanical thrombectomy between March 2016 and July 2016. Baseline clinical and imaging characteristics, recanalization rates, complications, and clinical outcomes were analyzed.
RESULTS RESULTS
Among the 60 patients included, 30 were treated using aspiration alone, 14 were treated using aspiration and then stent retriever as a rescue therapy, and 16 were treated using aspiration combined with a stent retriever straightaway. Successful recanalization (mTICI2b/3) was achieved in 85% patients and functional independence in 48.3%. We observed one intracranial perforation and one vertebral artery dissection. Symptomatic intracranial hemorrhage occurred in 5% and mortality in 21.7%.
CONCLUSION CONCLUSIONS
Endovascular stroke therapy using the AXS Catalyst catheter seems safe and effective, with similar performance than other reperfusion catheters.

Identifiants

pubmed: 30327929
doi: 10.1007/s00270-018-2093-y
pii: 10.1007/s00270-018-2093-y
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110-115

Auteurs

M Bretzner (M)

Department of Interventional Neuroradiology, University of Lille, Hopital Roger Salengro - CHU Lille, 59800, Lille, France.
INSERM U1171 - Degenerative and Vascular Cognitive Disorders, Lille, France.

L Estrade (L)

Department of Interventional Neuroradiology, University of Lille, Hopital Roger Salengro - CHU Lille, 59800, Lille, France.

M Ferrigno (M)

Department of Neurology, University of Lille, CHU Lille, Lille, France.
INSERM U1171 - Degenerative and Vascular Cognitive Disorders, Lille, France.

F Bala (F)

Department of Interventional Neuroradiology, University of Lille, Hopital Roger Salengro - CHU Lille, 59800, Lille, France.

F Boustia (F)

Department of Interventional Neuroradiology, University of Tours, CHU Tours, Tours, France.

A Kazemi (A)

Department of Interventional Neuroradiology, University of Lille, Hopital Roger Salengro - CHU Lille, 59800, Lille, France.

J P Pruvo (JP)

Department of Interventional Neuroradiology, University of Lille, Hopital Roger Salengro - CHU Lille, 59800, Lille, France.
INSERM U1171 - Degenerative and Vascular Cognitive Disorders, Lille, France.

H Henon (H)

Department of Neurology, University of Lille, CHU Lille, Lille, France.
INSERM U1171 - Degenerative and Vascular Cognitive Disorders, Lille, France.

N Bricout (N)

Department of Interventional Neuroradiology, University of Lille, Hopital Roger Salengro - CHU Lille, 59800, Lille, France. bricout.nicolas@gmail.com.

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Classifications MeSH