Biomimetic cofactors and methods for their recycling.

Biocatalysis Biomimetics NAD / metabolism Niacinamide / metabolism

Journal

Current opinion in chemical biology
ISSN: 1879-0402
Titre abrégé: Curr Opin Chem Biol
Pays: England
ID NLM: 9811312

Informations de publication

Date de publication:
04 2019
Historique:
received: 31 08 2018
revised: 30 09 2018
accepted: 02 10 2018
pubmed: 20 10 2018
medline: 18 12 2019
entrez: 19 10 2018
Statut: ppublish

Résumé

Nicotinamide cofactor biomimetics (NCBs) belong to a class of compounds that, as the name suggests, mimic the structures and functions of natural nicotinamide cofactors, namely nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate and their corresponding reduced forms. The first set of NCBs was discovered in the 1930s; these were initially used to study the chemical properties of this class of cofactors as well as understand nicotinamide binding of oxidoreductases. Since then, various NCBs, enzymes, and recycling systems have evolved and lately, new NCBs have been developed and used to run biocatalytic reactions.

Identifiants

DOI: 10.1016/j.cbpa.2018.10.003 PMID: 30336443
pubmed: 30336443
pii: S1367-5931(18)30142-X
doi: 10.1016/j.cbpa.2018.10.003
pii:
doi:

Substances chimiques

NAD 0U46U6E8UK
Niacinamide 25X51I8RD4

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

59-66

Informations de copyright

Copyright © 2018. Published by Elsevier Ltd.

Auteurs

Ioannis Zachos (I)

Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315 Straubing, Germany.

Claudia Nowak (C)

Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315 Straubing, Germany; Current address: Dr. Ebeling & Assoc. GmbH, Hamburg, Germany.

Volker Sieber (V)

Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315 Straubing, Germany; Catalysis Research Center, Technical University of Munich, Garching, Germany; Fraunhofer Institute of InterfacialBiotechnology (IGB), Bio-, Electro- and Chemo Catalysis (BioCat) Branch, Straubing, Germany; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Qld, Australia. Electronic address: sieber@tum.de.

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Biocatalyse › Biomimetic cofactors and methods for their recycling.
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Biotechnologie › Biomimétique › Biomimetic cofactors and methods for their recycling.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › NAD › Biomimetic cofactors and methods for their recycling.
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyridines › Acides nicotiniques › Nicotinamide › Biomimetic cofactors and methods for their recycling.