Lateral geniculate nucleus volumetry at 3T and 7T: Four different optimized magnetic-resonance-imaging sequences evaluated against a 7T reference acquisition.
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
01 02 2019
01 02 2019
Historique:
received:
18
12
2017
revised:
24
08
2018
accepted:
17
09
2018
pubmed:
21
10
2018
medline:
16
7
2019
entrez:
21
10
2018
Statut:
ppublish
Résumé
The lateral geniculate nucleus (LGN) is an essential nucleus of the visual pathway, occupying a small volume (60-160 mm In 31 healthy subjects, we obtained at 3 and 7 T the following MR sequences: PD-TSE, MPRAGE with white/grey matter signal nulled (WMn/GMn), and a motion-corrected segmented MPRAGE sequence with a resolution of 0.4 × 0.4 × 0.4 mm The reference acquisition provided a very sharp depiction of the LGN and an estimated mean LGN volume of 124 ± 3.3 mm WMn and GMn MPRAGE allow reliable LGN volume determination at both field strengths. The precise location and identification of the LGN (volume) can help to optimize neuroanatomical and neurophysiological studies, which involve the LGN structure. Our optimized imaging protocol may be used for clinical applications aiming at small nuclei volumetric and CNR quantification.
Identifiants
pubmed: 30342237
pii: S1053-8119(18)30831-0
doi: 10.1016/j.neuroimage.2018.09.046
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
399-409Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.