Stress Computed Tomography Perfusion Versus Fractional Flow Reserve CT Derived in Suspected Coronary Artery Disease: The PERFECTION Study.

Adenosine / administration & dosage Aged Computed Tomography Angiography Coronary Angiography / methods Coronary Artery Disease / diagnostic imaging Coronary Stenosis / diagnostic imaging Coronary Vessels / diagnostic imaging Databases, Factual Female Fractional Flow Reserve, Myocardial Humans Longitudinal Studies Male Middle Aged Multidetector Computed Tomography Myocardial Perfusion Imaging / methods Predictive Value of Tests Prospective Studies Reproducibility of Results Vasodilator Agents / administration & dosage

accuracy computed tomography coronary artery disease fractional flow reserve perfusion

Journal

JACC. Cardiovascular imaging

ISSN: 1876-7591

Titre abrégé: JACC Cardiovasc Imaging

Pays: United States

ID NLM: 101467978

Informations de publication

Date de publication:
08 2019

Historique:

received: 19 03 2018

revised: 16 08 2018

accepted: 17 08 2018

pubmed: 22 10 2018

medline: 25 3 2020

entrez: 22 10 2018

Statut: ppublish

Résumé

This study sought to compare the diagnostic accuracy of coronary computed tomography angiography (cCTA) with that of cCTA+fractional flow reserve derived from cCTA datasets (FFR FFR A total of 147 consecutive symptomatic patients scheduled for clinically indicated ICA+invasive FFR were evaluated with cCTA, FFR Vessel-based and patient-based sensitivity, specificity, and negative predictive values, and positive predictive values, and accuracy rates of cCTA were 99%, 76%, 100%, 61%, 82%, and 95%, 54%, 94%, 63%, 73%, respectively. cCTA+FFR FFR

Sections du résumé

OBJECTIVES

This study sought to compare the diagnostic accuracy of coronary computed tomography angiography (cCTA) with that of cCTA+fractional flow reserve derived from cCTA datasets (FFR

BACKGROUND

FFR

METHODS

A total of 147 consecutive symptomatic patients scheduled for clinically indicated ICA+invasive FFR were evaluated with cCTA, FFR

RESULTS

Vessel-based and patient-based sensitivity, specificity, and negative predictive values, and positive predictive values, and accuracy rates of cCTA were 99%, 76%, 100%, 61%, 82%, and 95%, 54%, 94%, 63%, 73%, respectively. cCTA+FFR

CONCLUSIONS

FFR

Identifiants

DOI: 10.1016/j.jcmg.2018.08.023 PMID: 30343073

pubmed: 30343073

pii: S1936-878X(18)30751-4

doi: 10.1016/j.jcmg.2018.08.023

pii:

doi:

Substances chimiques

Vasodilator Agents 0

Adenosine K72T3FS567

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

1487-1497

Commentaires et corrections

Type : CommentIn