Peptides and Astroglia Improve the Regenerative Capacity of Alginate Gels in the Injured Spinal Cord.

Alginates / chemistry Animals Axons Biocompatible Materials / chemistry Guided Tissue Regeneration / methods Humans Hydrogels / chemistry Peptides / chemistry Spinal Cord Injuries / therapy
alginate astroglia biomaterial cell transplantation regeneration spinal cord injury

Journal

Tissue engineering. Part A
ISSN: 1937-335X
Titre abrégé: Tissue Eng Part A
Pays: United States
ID NLM: 101466659

Informations de publication

Date de publication:
04 2019
Historique:
pubmed: 24 10 2018
medline: 31 12 2019
entrez: 24 10 2018
Statut: ppublish

Résumé

Axonal bridging across a lesion in the injured spinal cord requires a growth substrate and guidance cues. Using alginate hydrogels with capillary channels we show that poly-l-ornithine and laminin can be stably bound and improve cell adhesion and neurite growth

Identifiants

DOI: 10.1089/ten.TEA.2018.0082 PMID: 30351234
pubmed: 30351234
doi: 10.1089/ten.TEA.2018.0082
doi:

Substances chimiques

Alginates 0
Biocompatible Materials 0
Hydrogels 0
Peptides 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

522-537

Auteurs

Thomas Schackel (T)

1 Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany.

Prateek Kumar (P)

2 Department of Neurological Surgery and Goodman Campbell Brain and Spine, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana.

Manuel Günther (M)

1 Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany.

Shengwen Liu (S)

1 Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany.
3 Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.

Manuel Brunner (M)

4 Department of Physical and Theoretical Chemistry, University of Regensburg, Regensburg, Germany.

Beatrice Sandner (B)

1 Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany.

Radhika Puttagunta (R)

1 Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany.

Rainer Müller (R)

4 Department of Physical and Theoretical Chemistry, University of Regensburg, Regensburg, Germany.

Norbert Weidner (N)

1 Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany.

Armin Blesch (A)

1 Spinal Cord Injury Center, Heidelberg University Hospital, Heidelberg, Germany.
2 Department of Neurological Surgery and Goodman Campbell Brain and Spine, Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana.

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Classifications MeSH

questionsmedicales.fr › Glucides › Polyosides › Alginates › Peptides and Astroglia Improve the...
questionsmedicales.fr › Eucaryotes › Animaux › Peptides and Astroglia Improve the...
questionsmedicales.fr › Cellules › Neurones › Neurofibres › Axones › Peptides and Astroglia Improve the...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Matériaux biocompatibles › Peptides and Astroglia Improve the...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie reconstructive › Régénération tissulaire guidée › Peptides and Astroglia Improve the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Peptides and Astroglia Improve the...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Peptides and Astroglia Improve the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptides and Astroglia Improve the...
questionsmedicales.fr › Plaies et blessures › Traumatismes de la moelle épinière › Peptides and Astroglia Improve the...