Repeated SBRT for in- and out-of-field recurrences in the liver.
Wiederholte SBRT bei In- und Out-of-field Rezidiven der Leber.
Adult
Aged
Aged, 80 and over
Bile Duct Neoplasms
/ radiotherapy
Carcinoma, Hepatocellular
/ radiotherapy
Cholangiocarcinoma
/ radiotherapy
Dose Fractionation, Radiation
Female
Follow-Up Studies
Germany
Humans
Liver Neoplasms
/ radiotherapy
Male
Middle Aged
Neoplasm Recurrence, Local
/ radiotherapy
Radiosurgery
/ methods
Retreatment
Cholangiocarcinoma
Hepatocellular carcinoma
Liver metastases
Re-SBRT
Stereotactic body radiotherapy
Journal
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
ISSN: 1439-099X
Titre abrégé: Strahlenther Onkol
Pays: Germany
ID NLM: 8603469
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
25
04
2018
accepted:
09
10
2018
pubmed:
26
10
2018
medline:
21
11
2019
entrez:
25
10
2018
Statut:
ppublish
Résumé
To evaluate the feasibility and toxicity profile of repeated stereotactic body radiotherapy (SBRT) for recurrent primary or secondary liver tumors. Consecutive patients with primary (hepatocellular carcinoma [HCC] or cholangiocarcinoma [CCC]) or secondary liver cancer (LM), with intrahepatic recurrence or progression after SBRT, underwent re-SBRT in 3 to 12 fractions with a median time of 15 (range 2-66) months between treatments. In all, 24 patients which were previously treated with SBRT (30 lesions) were retreated with SBRT for "in- and out-of-field" recurrences (2nd SBRT: n = 28, 3rd SBRT: n = 2). The median follow-up after re-irradiation was 14 months. The median prescribed dose for the first SBRT was 46.5 (range 33-66 Gy, EQD2 Repeated liver SBRT is feasible, without excessive liver toxicity, when there is no considerable overlapping with pre-irradiated portions of the stomach or bowel and enough time for the liver to regenerate.
Identifiants
pubmed: 30353350
doi: 10.1007/s00066-018-1385-0
pii: 10.1007/s00066-018-1385-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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