Children with unilateral cochlear nerve canal stenosis have bilateral cochleovestibular anomalies.


Journal

The Laryngoscope
ISSN: 1531-4995
Titre abrégé: Laryngoscope
Pays: United States
ID NLM: 8607378

Informations de publication

Date de publication:
10 2019
Historique:
received: 04 11 2017
revised: 18 07 2018
accepted: 16 08 2018
pubmed: 26 10 2018
medline: 5 11 2019
entrez: 25 10 2018
Statut: ppublish

Résumé

To investigate the cochleovestibular apparatus bilaterally in children with isolated unilateral bony cochlear nerve canal (bCNC) stenosis. Retrospective review. Imaging studies of children with unilateral bCNC stenosis (<1.0 mm) on computed tomography imaging (N = 36) were compared with controls imaged due to trauma without temporal bone injury (N = 32). Twenty-six measurements were obtained in each ear, assessing the bony internal auditory canal (IAC), cochlea, and vestibular end-organs, and were analyzed using one-way analysis of variance for intersubject comparisons and paired t tests for intrasubject comparisons with a Bonferroni adjustment for multiple comparisons (P = .0006). Patients with bCNC stenosis had a smaller IAC (P < .000) and cochlea (P < .000) on the stenotic side as compared with controls. Although the vestibular end-organ was also smaller in bCNC ears, this difference was not significant. The contralateral ear also had a smaller bCNC (P < .000) and cochlea (P < .000) as compared with controls, although to a lesser degree than the stenotic side. Children with unilateral bCNC stenosis have abnormal biometry of both the cochlea and the vestibular end-organ in the affected and the normal contralateral ear as compared with controls. 3b Laryngoscope, 129:2403-2408, 2019.

Identifiants

pubmed: 30353559
doi: 10.1002/lary.27559
doi:

Types de publication

Evaluation Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2403-2408

Subventions

Organisme : CIHR
Pays : Canada

Informations de copyright

© 2018 The American Laryngological, Rhinological and Otological Society, Inc.

Références

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Auteurs

Luis D Vilchez-Madrigal (LD)

Department of Otolaryngology-Head and Neck Surgery, National Children's Hospital, San Jose, Costa Rica.

Susan I Blaser (SI)

Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Department of Diagnostic Imaging, Division of Neuroradiology, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Nikolaus E Wolter (NE)

Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Adrian L James (AL)

Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Blake C Papsin (BC)

Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Archie's Cochlear Implant Laboratory, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Karen A Gordon (KA)

Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Archie's Cochlear Implant Laboratory, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Department of Communication Disorders, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Sharon L Cushing (SL)

Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Archie's Cochlear Implant Laboratory, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Evan J Propst (EJ)

Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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