Cherry consumption out of season alters lipid and glucose homeostasis in normoweight and cafeteria-fed obese Fischer 344 rats.
Cherry consumption
Circannual rhythms
Metabolic homeostasis
Polyphenols
Seasonal fruits
Xenohormesis theory
Journal
The Journal of nutritional biochemistry
ISSN: 1873-4847
Titre abrégé: J Nutr Biochem
Pays: United States
ID NLM: 9010081
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
03
07
2018
revised:
30
07
2018
accepted:
12
09
2018
pubmed:
26
10
2018
medline:
9
4
2020
entrez:
26
10
2018
Statut:
ppublish
Résumé
The xenohormesis theory postulates that animals, through the consumption of chemical cues, mainly polyphenols, synthetized by plants, are able to favorably adapt to changing environmental conditions. We hypothesized that the intake of fruits with a seasonally distinctive phenotype (in terms of bioactive compounds) produced a metabolic response that depends on mammals' circannual rhythms and that fruit intake out of season can lead to a disruption in characteristic seasonal metabolism. Fischer 344 rats were chronically exposed to short (L6, 6 h light/day) and long (L18, 18 h light/day) photoperiods in order to simulate autumn and spring seasons, respectively, and were fed either a standard diet (STD) or an obesogenic cafeteria diet (CAF) and orally treated with either vehicle or 100 mg kg
Identifiants
pubmed: 30359863
pii: S0955-2863(18)30651-X
doi: 10.1016/j.jnutbio.2018.09.013
pii:
doi:
Substances chimiques
Fatty Acids
0
Proteins
0
Akt2 protein, rat
EC 2.7.11.1
Proto-Oncogene Proteins c-akt
EC 2.7.11.1
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
72-86Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.