Highly porous of hydroxyethyl cellulose biocomposite scaffolds for tissue engineering.
Hydroxyethyl cellulose
Porous scaffold
Skin tissue engineering
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
01 Feb 2019
01 Feb 2019
Historique:
received:
04
07
2018
revised:
16
10
2018
accepted:
22
10
2018
pubmed:
27
10
2018
medline:
6
4
2019
entrez:
27
10
2018
Statut:
ppublish
Résumé
This study is focusing to develop a porous biocompatible scaffold using hydroxyethyl cellulose (HEC) and poly (vinyl alcohol) (PVA) with improved cellular adhesion profiles and stability. The combination of HEC and PVA were synthesized using freeze-drying technique and characterized using SEM, ATR-FTIR, TGA, DSC, and UTM. Pore size of HEC/PVA (2-40 μm) scaffolds showed diameter in a range of both pure HEC (2-20 μm) and PVA (14-70 μm). All scaffolds revealed high porosity above 85%. The water uptake of HEC was controlled by PVA cooperation in the polymer matrix. After 7 days, all blended scaffolds showed low degradation rate with the increased of PVA composition. The FTIR and TGA results explicit possible chemical interactions and mass loss of blended scaffolds, respectively. The T
Identifiants
pubmed: 30365990
pii: S0141-8130(18)33357-9
doi: 10.1016/j.ijbiomac.2018.10.156
pii:
doi:
Substances chimiques
Biocompatible Materials
0
Cellulose
9004-34-6
hydroxyethylcellulose
9004-62-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
562-571Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.