Prospective evaluation of the performances of narrow-band imaging flexible videoscopy relative to white-light imaging flexible videoscopy, in patients scheduled for transurethral resection of a primary NMIBC.
Endoscopy
Narrow-band imaging
Sensitivity
Specificity
Urinary bladder neoplasms
Journal
World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
16
05
2018
accepted:
19
10
2018
pubmed:
28
10
2018
medline:
20
2
2020
entrez:
28
10
2018
Statut:
ppublish
Résumé
To evaluate on a lesion-by-lesion basis Narrow-Band Imaging flexible videoscopy (NBI-FV) in the detection of cancer compared to White-Light Imaging flexible videoscopy (WLI-FV). WLI-FV and NBI-FV were sequentially performed in patients scheduled for TURBT for primary bladder cancer. Suspicious findings were individually harvested and characterized under WLI-FV (suspicious/non-suspicious) and NBI-FV (5-point Likert scale) and pathology. The primary objective was to determine if NBI-FV informed at least 20% more cancer lesions than WLI-FV (Relative true-positive rate > 1.19). A minimum of 120 specimens was to be analyzed to reach 90% power. Of 147 specimens taken in 68 patients, 101 were found suspicious under WLI-FV and 64 (64/101, 63.4%) confirmed as cancer. Of the 46 lesions undetected by WLI-VF, 16 were found positive for cancer (16/46, 34.8%). For NBI-FV, a significant increase in positive samples was observed with increments in Likert scale (p < 0.0002). Relative true-positive rate was 1.22 (95% CI 1.12-1.39)-NBI-FV detected 22% more cancer lesions compared to WLI-FV. Relative false-positive rate was 1.35 (95% CI 1.19-1.59). Researching alterations in mucosa and microvasculature by narrow-band imaging flexible videoscopy augmented by 22% the detection of cancer foci and contributed to the objective of complete resection of all visible lesions. Conversely, it entailed a 35% increase in false-positive results compared to white-light imaging, although the structured analysis of narrow-band imaging findings might be used to grade suspicion according to the Likert scale and balance the risk of a false-positive result to the benefit of demonstrating cancer.
Identifiants
pubmed: 30367204
doi: 10.1007/s00345-018-2537-7
pii: 10.1007/s00345-018-2537-7
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1615-1621Références
Sylvester RJ, van der Meijden AP, Oosterlinck W, Witjes JA, Bouffioux C, Denis L, Newling DW, Kurth K (2006) Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. Eur Urol 49(3):466–477 (discussion 75-7)
doi: 10.1016/j.eururo.2005.12.031
Power NE, Izawa J (2016) Comparison of guidelines on non-muscle invasive bladder cancer (EAU, CUA, AUA, NCCN, NICE). Bladder Cancer 2(1):27–36
doi: 10.3233/BLC-150034
Brausi M, Collette L, Kurth K, van der Meijden AP, Oosterlinck W, Witjes JA, Newling D, Bouffioux C, Sylvester RJ, Group EG-UTCC (2002) Variability in the recurrence rate at first follow-up cystoscopy after TUR in stage Ta T1 transitional cell carcinoma of the bladder: a combined analysis of seven EORTC studies. Eur Urol 41(5):523–531
doi: 10.1016/S0302-2838(02)00068-4
Babjuk M, Bohle A, Burger M, Capoun O, Cohen D, Comperat EM, Hernandez V, Kaasinen E, Palou J, Roupret M, van Rhijn BW, Shariat SF, Soukup V, Sylvester RJ, Zigeuner R (2017) EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2016. Eur Urol 71(3):447–461
doi: 10.1016/j.eururo.2016.05.041
Folkman J, Merler E, Abernathy C, Williams G (1971) Isolation of a tumor factor responsible for angiogenesis. J Exp Med 133(2):275–288
doi: 10.1084/jem.133.2.275
Gono K, Obi T, Yamaguchi M, Ohyama N, Machida H, Sano Y, Yoshida S, Hamamoto Y, Endo T (2004) Appearance of enhanced tissue features in narrow-band endoscopic imaging. J Biomed Opt 9(3):568–577
doi: 10.1117/1.1695563
Bryan RTBL, Wallace DM (2008) Narrow-band imaging flexible cystoscopy in the detection of recurrent urothelial cancer of the bladder. BJU Int 101:702–705 (discussion 5–6)
doi: 10.1111/j.1464-410X.2007.07317.x
Cauberg EC, Kloen S, Visser M, de la Rosette JJ, Babjuk M, Soukup V, Pesl M, Duskova J, de Reijke TM (2010) Narrow band imaging cystoscopy improves the detection of non-muscle-invasive bladder cancer. Urology 76(3):658–663
doi: 10.1016/j.urology.2009.11.075
Jones S, Larchian W (2012) Non-muscle-invasive bladder cancer (Ta, T1, and CIS). In: Kavoussi LR, Novick AC, Partin AW, Peters CA (eds) Campbell-walsh urology tenth edition IV. Elsevier Saunders, Philadelphia, pp 2335–2354
doi: 10.1016/B978-1-4160-6911-9.00081-5
Ragsdale C, Hreha H, Hardesty JS, Yune JJ, Chan PJ, Siddighi S (2017) What is the best lens angle for rigid diagnostic cystoscopy? A comparison of 30-degree and 70-degree lenses. Female Pelvic Med Reconstr Surg 24(5):371–374
doi: 10.1097/SPV.0000000000000473
NIH’s definition of a clinical trial (2018) https://grants.nih.gov/policy/clinical-trials/definition.htm Bethesda, Maryland 20892 (USA) [cited 26 Mar 2018]
Shen YJ, Zhu YP, Ye DW, Yao XD, Zhang SL, Dai B, Zhang HL, Zhu Y (2012) Narrow-band imaging flexible cystoscopy in the detection of primary non-muscle invasive bladder cancer: a “second look” matters? Int Urol Nephrol 44(2):451–457
doi: 10.1007/s11255-011-0036-5
Mostofi FK, Sobin LH, Torloni H (1973) Histological typing of urinary bladder tumours. World Health Organization, Geneva, p 1973
Kausch I, Sommerauer M, Montorsi F, Stenzl A, Jacqmin D, Jichlinski P, Jocham D, Ziegler A, Vonthein R (2010) Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies. Eur Urol 57(4):595–606
doi: 10.1016/j.eururo.2009.11.041
Chock CIL, Berry G, Glasziou P (2010) Comparing dichotomous screening tests when individuals negative on both tests are not verified. J Clin Epidemiol 50(11):1211–1217
doi: 10.1016/S0895-4356(97)00122-4
Agresti A, Coull B (1998) Approximate is better than “exact” for interval estimation of binomial proportions. Am Stat 52(2):119–126
Alonzo TA, Pepe MS, Moskowitz CS (2002) Sample size calculations for comparative studies of medical tests for detecting presence of disease. Stat Med 21(6):835–852
doi: 10.1002/sim.1058
Alonzo TA, Kittelson JM (2006) A novel design for estimating relative accuracy of screening tests when complete disease verification is not feasible. Biometrics 62(2):605–612
doi: 10.1111/j.1541-0420.2005.00445.x
Xiong Y, Li J, Ma S, Ge J, Zhou L, Li D, Chen Q (2017) A meta-analysis of narrow band imaging for the diagnosis and therapeutic outcome of non-muscle invasive bladder cancer. PLoS One 12(2):e0170819
doi: 10.1371/journal.pone.0170819
Herr HW, Donat SM (2008) A comparison of white-light cystoscopy and narrow-band imaging cystoscopy to detect bladder tumour recurrences. BJU Int 102(9):1111–1114
doi: 10.1111/j.1464-410X.2008.07846.x
Tatsugami K, Kuroiwa K, Kamoto T, Nishiyama H, Watanabe J, Ishikawa S, Shinohara N, Sazawa A, Fukushima S, Naito S (2010) Evaluation of narrow-band imaging as a complementary method for the detection of bladder cancer. J Endourol 24(11):1807–1811
doi: 10.1089/end.2010.0055
Gatenby RA, Gillies RJ (2008) A microenvironmental model of carcinogenesis. Nat Rev Cancer 8(1):56–61
doi: 10.1038/nrc2255
Lee JY, Cho KS, Kang DH, Jung HD, Kwon JK, Oh CK, Ham WS, Choi YD (2015) A network meta-analysis of therapeutic outcomes after new image technology-assisted trans-urethral resection for non-muscle invasive bladder cancer: 5-aminolaevulinic acid fluorescence vs hexylaminolevulinate fluorescence vs narrow band imaging. BMC Cancer 15:566
doi: 10.1186/s12885-015-1571-8
Ye Z, Hu J, Song X, Li F, Zhao X, Chen S, Wang X, He D, Fan J, Ye D, Xing J, Pan T, Wang D (2015) A comparison of NBI and WLI cystoscopy in detecting non-muscle-invasive bladder cancer: a prospective, randomized and multi-center study. Sci Rep 5:10905
doi: 10.1038/srep10905
Curtius K, Wright NA, Graham TA (2018) An evolutionary perspective on field cancerization. Nat Rev Cancer 18(1):19–32
doi: 10.1038/nrc.2017.102
Soukup V, Capoun O, Cohen D, Hernandez V, Babjuk M, Burger M, Comperat E, Gontero P, Lam T, MacLennan S, Mostafid AH, Palou J, van Rhijn BWG, Roupret M, Shariat SF, Sylvester R, Yuan Y, Zigeuner R (2017) Prognostic performance and reproducibility of the 1973 and 2004/2016 World Health Organization grading classification systems in non-muscle-invasive bladder cancer: a European association of urology non-muscle invasive bladder cancer guidelines panel systematic review. Eur Urol 72(5):801–813
doi: 10.1016/j.eururo.2017.04.015
Lopez-Beltran A, Marques RC, Montironi R, Reymundo C, Fonseca J, Cheng L (2015) Dysplasia and carcinoma in situ of the urinary bladder. Anal Quant Cytopathol Histpathol 37(1):29–38
pubmed: 26072632
Naito S, Algaba F, Babjuk M, Bryan RT, Sun YH, Valiquette L, de la Rosette J (2016) The clinical research office of the endourological society (CROES) Multicentre randomised trial of narrow band imaging-assisted transurethral resection of bladder tumour (TURBT) versus conventional white light imaging-assisted TURBT in primary non-muscle-invasive bladder cancer patients: trial protocol and 1-year results. Eur Urol 70(3):506–515 (Group CNBIGS)
doi: 10.1016/j.eururo.2016.03.053