Adolescent-Onset Hidradenitis Suppurativa: Prevalence, Risk Factors and Disease Features.


Journal

Dermatology (Basel, Switzerland)
ISSN: 1421-9832
Titre abrégé: Dermatology
Pays: Switzerland
ID NLM: 9203244

Informations de publication

Date de publication:
2019
Historique:
received: 06 06 2018
accepted: 03 09 2018
pubmed: 29 10 2018
medline: 29 3 2019
entrez: 29 10 2018
Statut: ppublish

Résumé

Hidradenitis suppurativa (HS) is a chronic inflammatory and destructive skin disorder. Early diagnosis and treatment are critical to stop its progression. Data concerning adolescent-onset HS are scarce. The aims of this study are to describe the prevalence of adolescent-onset HS and to explore potential risk factors and the disease features of these patients. A cross-sectional study including 134 patients was performed. Adolescent-onset HS occurred in 51.5% (69/134) of patients. Adolescent-onset HS was associated with female sex, positive family history, presence of pilonidal sinus, acne conglobata, longer disease duration and a worse perception of disease severity. Adolescent-onset HS might be more frequent than previously reported. Female sex, positive family history and the presence of elements of the follicular occlusion tetrad identify individuals with a higher risk of early onset. These patients experience a longer disease duration and perceive their disease as severer.

Sections du résumé

BACKGROUND/AIMS OBJECTIVE
Hidradenitis suppurativa (HS) is a chronic inflammatory and destructive skin disorder. Early diagnosis and treatment are critical to stop its progression. Data concerning adolescent-onset HS are scarce. The aims of this study are to describe the prevalence of adolescent-onset HS and to explore potential risk factors and the disease features of these patients.
PATIENTS AND METHODS METHODS
A cross-sectional study including 134 patients was performed.
RESULTS RESULTS
Adolescent-onset HS occurred in 51.5% (69/134) of patients. Adolescent-onset HS was associated with female sex, positive family history, presence of pilonidal sinus, acne conglobata, longer disease duration and a worse perception of disease severity.
CONCLUSION CONCLUSIONS
Adolescent-onset HS might be more frequent than previously reported. Female sex, positive family history and the presence of elements of the follicular occlusion tetrad identify individuals with a higher risk of early onset. These patients experience a longer disease duration and perceive their disease as severer.

Identifiants

pubmed: 30368494
pii: 000493465
doi: 10.1159/000493465
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

45-50

Informations de copyright

© 2018 S. Karger AG, Basel.

Auteurs

Alejandro Molina-Leyva (A)

Hidradenitis Suppurativa Clinic, Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spainalejandromolinaleyva@gmail.com.

Carlos Cuenca-Barrales (C)

Dermatology Department, Hospital Universitario San Cecilio, Granada, Spain.

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Classifications MeSH