Kidney diseases associated with Waldenström macroglobulinemia.

MPGN Waldenström macroglobulinemia amyloidosis onconephrology paraproteinemia

Journal

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
ISSN: 1460-2385
Titre abrégé: Nephrol Dial Transplant
Pays: England
ID NLM: 8706402

Informations de publication

Date de publication:
01 10 2019
Historique:
received: 02 05 2018
accepted: 11 09 2018
pubmed: 1 11 2018
medline: 10 4 2020
entrez: 1 11 2018
Statut: ppublish

Résumé

Waldenström macroglobulinemia (WM) is a rare B-cell lymphoma characterized by lymphoplasmacytic cell infiltration in the bone marrow and other organs and the presence of a monoclonal immunoglobulin M protein in the serum. Although uncommon, several kidney diseases have been associated with WM. In addition to kidney diseases related to lymphoplasmacytic lymphoma infiltration, a variety of glomerular and tubular lesions have been described in patients with WM. Immunoglobulin light chain (AL) amyloidosis and cryoglobulinemic glomerulonephritis are the two predominant glomerular pathologies seen in WM. In this article we review the kidney diseases associated with WM. We also briefly review some nephrotoxicities of novel chemotherapeutic and targeted therapies used for the treatment of WM.

Identifiants

pubmed: 30380110
pii: 5151291
doi: 10.1093/ndt/gfy320
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1644-1652

Informations de copyright

© The Author(s) 2018. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Auteurs

Nupur N Uppal (NN)

Division of Kidney Diseases and Hypertension, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Divya Monga (D)

Division of Nephrology, University of Mississippi Medical Center, Jackson, MS, USA.

Melchiore A Vernace (MA)

Nephrology-Hypertension Specialists, Doylestown, PA, USA.

Khurram Mehtabdin (K)

Division of Kidney Diseases and Hypertension, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Hitesh H Shah (HH)

Division of Kidney Diseases and Hypertension, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Vanesa Bijol (V)

Department of Pathology, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

Kenar D Jhaveri (KD)

Division of Kidney Diseases and Hypertension, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.

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Classifications MeSH