Carotid chemoreceptors have a limited role in mediating the hyperthermia-induced hyperventilation in exercising humans.
heat stroke
peripheral chemoreceptors
respiratory alkalosis
selective brain cooling
Journal
Journal of applied physiology (Bethesda, Md. : 1985)
ISSN: 1522-1601
Titre abrégé: J Appl Physiol (1985)
Pays: United States
ID NLM: 8502536
Informations de publication
Date de publication:
01 02 2019
01 02 2019
Historique:
pubmed:
2
11
2018
medline:
28
4
2020
entrez:
2
11
2018
Statut:
ppublish
Résumé
Hyperthermia causes hyperventilation at rest and during exercise. We previously reported that carotid chemoreceptors partly contribute to the hyperthermia-induced hyperventilation at rest. However, given that a hyperthermia-induced hyperventilation markedly differs between rest and exercise, the results obtained at rest may not be representative of the response in exercise. Therefore, we evaluated whether carotid chemoreceptors contribute to hyperthermia-induced hyperventilation in exercising humans. Eleven healthy young men (23 ± 2 yr) cycled in the heat (37°C) at a fixed submaximal workload equal to ~55% of the individual's predetermined peak oxygen uptake (moderate intensity). To suppress carotid chemoreceptor activity, 30-s hyperoxia breathing (100% O
Identifiants
pubmed: 30382804
doi: 10.1152/japplphysiol.00562.2018
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM