Ductal Carcinoma in Situ Biomarkers in a Precision Medicine Era: Current and Future Molecular-Based Testing.
Journal
The American journal of pathology
ISSN: 1525-2191
Titre abrégé: Am J Pathol
Pays: United States
ID NLM: 0370502
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
26
06
2018
revised:
09
08
2018
accepted:
30
08
2018
pubmed:
6
11
2018
medline:
12
2
2020
entrez:
3
11
2018
Statut:
ppublish
Résumé
Historically, ductal carcinoma in situ (DCIS) of the breast has been managed aggressively with surgery and radiotherapy because of a risk of progression to invasive ductal carcinoma. However, this treatment paradigm has been challenged by overtreatment concerns and evidence that suggests that DCIS can be stratified according to risk of recurrence or risk of progression to invasive disease. Traditional methods of risk stratification include histologic grade and hormone receptor status. Recent technological advancements have enabled an era of precision medicine, where DCIS can be molecularly analyzed by tools, such as next-generation DNA and RNA sequencing, to identify molecular biomarkers for risk stratification. These findings have led to the development of tools such as the Oncotype DX Breast DCIS Score, a gene expression-based assay with the potential to prevent overtreatment in low-risk disease.
Identifiants
pubmed: 30385093
pii: S0002-9440(18)30558-3
doi: 10.1016/j.ajpath.2018.08.020
pmc: PMC6521891
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
956-965Subventions
Organisme : NCI NIH HHS
ID : F30 CA216966
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA200994
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA211869
Pays : United States
Informations de copyright
Copyright © 2019 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.
Références
J Natl Cancer Inst. 2003 Nov 19;95(22):1692-702
pubmed: 14625260
J Natl Cancer Inst. 1998 Sep 16;90(18):1371-88
pubmed: 9747868
Mol Cell Proteomics. 2006 Oct;5(10):1799-810
pubmed: 16844681
Nat Clin Pract Oncol. 2006 Mar;3(3):138-51
pubmed: 16520804
Cell. 2012 May 25;149(5):994-1007
pubmed: 22608083
Cell. 2015 Oct 8;163(2):506-19
pubmed: 26451490
Dev Cell. 2010 Jun 15;18(6):884-901
pubmed: 20627072
Clin Cancer Res. 1997 Nov;3(11):1949-58
pubmed: 9815584
Cell. 2009 Nov 25;139(5):891-906
pubmed: 19931152
Cancer Res. 2002 Nov 15;62(22):6667-73
pubmed: 12438265
N Engl J Med. 2015 Feb 26;372(9):793-5
pubmed: 25635347
Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4153-4158
pubmed: 28377514
Mol Oncol. 2013 Oct;7(5):859-69
pubmed: 23890733
J Clin Oncol. 2013 May 20;31(15):1815-24
pubmed: 23589546
Genome Biol. 2014;15(8):435
pubmed: 25146004
Cell. 2005 May 6;121(3):335-48
pubmed: 15882617
Nature. 2012 Jul 26;487(7408):500-4
pubmed: 22763439
Nat Genet. 2013 Apr;45(4):353-61, 361e1-2
pubmed: 23535729
Nat Med. 2011 Aug 07;17(9):1109-15
pubmed: 21822285
J Natl Cancer Inst. 2013 May 15;105(10):701-10
pubmed: 23641039
Clin Epigenetics. 2015 Jul 25;7:75
pubmed: 26213588
J Exp Med. 2018 Mar 5;215(3):895-910
pubmed: 29436393
Genome Biol. 2014 Aug 30;15(8):452
pubmed: 25222669
Cancer Res. 2010 Jul 15;70(14):5674-8
pubmed: 20551053
J Clin Oncol. 2016 Nov 20;34(33):3963-3968
pubmed: 27621393
Breast Cancer Res Treat. 2003 May;79(2):187-98
pubmed: 12825853
Cancer Res. 2012 Sep 1;72(17):4574-86
pubmed: 22751464
Eur J Surg Oncol. 2004 Apr;30(3):243-7
pubmed: 15028303
Breast Cancer Res Treat. 2013 Jun;139(2):453-60
pubmed: 23624751
J Hum Genet. 2014 Dec;59(12):649-54
pubmed: 25296578
Breast. 2016 Feb;25:57-61
pubmed: 26612082
Breast Cancer Res Treat. 2010 Oct;123(3):757-65
pubmed: 20033484
Sci Rep. 2017 Oct 27;7(1):14196
pubmed: 29079769
Breast Cancer Res. 2006;8(2):204
pubmed: 16677423
Lancet. 1999 Jun 12;353(9169):1993-2000
pubmed: 10376613
Cancer Cell. 2004 Jul;6(1):17-32
pubmed: 15261139
Cancer. 2014 May 1;120(9):1329-37
pubmed: 24477928
CA Cancer J Clin. 2018 Jan;68(1):7-30
pubmed: 29313949
Science. 2013 Mar 29;339(6127):1546-58
pubmed: 23539594
Breast Cancer Res Treat. 2012 Jun;133(3):889-98
pubmed: 22052326
J Natl Cancer Inst. 2017 Apr 1;109(4):
pubmed: 30053207
Nat Rev Clin Oncol. 2015 Dec;12(12):693-704
pubmed: 26196250
Nature. 2012 Oct 4;490(7418):61-70
pubmed: 23000897
Breast Cancer Res Treat. 2015 Jul;152(2):389-98
pubmed: 26119102
Nature. 2009 Oct 22;461(7267):1084-91
pubmed: 19847259
Virchows Arch. 2011 Jan;458(1):73-84
pubmed: 21120523
Nature. 2012 Jun 20;486(7403):405-9
pubmed: 22722202
J Cancer. 2011 May 01;2:232-61
pubmed: 21552384
J Surg Oncol. 2015 Jun;111(8):935-40
pubmed: 26031501
Breast Cancer Res Treat. 2015 Aug;153(1):101-21
pubmed: 26255059
JAMA. 2015 Jun 2;313(21):2119-20
pubmed: 25928209
Genome Res. 2013 Jul;23(7):1097-108
pubmed: 23568837
Nat Rev Genet. 2016 May 17;17(6):333-51
pubmed: 27184599
Mol Cell Biol. 2008 Nov;28(22):6773-84
pubmed: 18794355
J Oncol. 2012;2012:584219
pubmed: 22811710
Cancer. 2011 Aug 15;117(16):3650-7
pubmed: 21319154
Sci Rep. 2016 Feb 12;6:21043
pubmed: 26868906
JAMA. 1978 May 5;239(18):1863-7
pubmed: 205686
J Clin Oncol. 2015 Nov 20;33(33):3938-44
pubmed: 26371148
Breast Cancer Res Treat. 2006 May;97(2):135-44
pubmed: 16319971
Am J Pathol. 2017 Jul;187(7):1648-1655
pubmed: 28634007
J Theor Biol. 2005 Jan 21;232(2):179-89
pubmed: 15530488
Eur J Cancer. 2001 Aug;37(12):1514-22
pubmed: 11506959
Breast Cancer Res. 2010;12(1):R3
pubmed: 20056007
Lancet. 2007 Aug 11;370(9586):485-92
pubmed: 17693177
Am J Surg. 2006 Jul;192(1):68-71
pubmed: 16769278
J Natl Cancer Inst. 2010 May 5;102(9):627-37
pubmed: 20427430
Ann Surg Oncol. 2017 Mar;24(3):660-668
pubmed: 27704370
Cancer Res. 2015 Sep 15;75(18):3980-90
pubmed: 26249178
Nature. 2011 Jun 08;475(7355):222-5
pubmed: 21654748
Nat Med. 2015 Nov;21(11):1253-61
pubmed: 26540387
Br J Cancer. 2011 Jan 4;104(1):120-7
pubmed: 21139586
Cell. 2013 Mar 28;153(1):17-37
pubmed: 23540688
Nat Med. 2015 Jul;21(7):751-9
pubmed: 26099045
Breast Cancer Res. 2009;11(1):R7
pubmed: 19187537
Nat Rev Cancer. 2002 Mar;2(3):161-74
pubmed: 11990853
Cancer. 2005 Jun 15;103(12):2481-4
pubmed: 15884091
Nat Med. 2017 Mar;23(3):376-385
pubmed: 28165479
Nature. 2012 Apr 04;486(7403):395-9
pubmed: 22495314
Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3372-7
pubmed: 19218449
Mod Pathol. 2017 Jul;30(7):952-963
pubmed: 28338653
Int J Cancer. 2003 Dec 20;107(6):970-5
pubmed: 14601057
Mod Pathol. 2015 Sep;28(9):1167-73
pubmed: 26111975
Lancet. 2003 Oct 4;362(9390):1154; author reply 1155-6
pubmed: 14550707
J Pathol. 2017 Jan;241(2):208-218
pubmed: 27861897
J Clin Oncol. 2006 Jul 20;24(21):3381-7
pubmed: 16801628
Mod Pathol. 2018 Apr;31(4):562-568
pubmed: 29243740
Breast Cancer. 2015 Sep;22(5):529-35
pubmed: 24402639
Cancer Cell. 2016 Apr 11;29(4):452-463
pubmed: 27070700
Am J Transl Res. 2016 Nov 15;8(11):4994-5004
pubmed: 27904700
Clin Cancer Res. 2014 May 1;20(9):2264-75
pubmed: 24599935