Increasing mixed venous oxygen saturation is a predictor of improved renal function after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension.
Aged
Angiography
Angioplasty, Balloon
/ methods
Cardiac Catheterization
Chronic Disease
Echocardiography
Female
Follow-Up Studies
Glomerular Filtration Rate
/ physiology
Humans
Hypertension, Pulmonary
/ etiology
Male
Middle Aged
Oxygen
/ metabolism
Oxygen Consumption
Prognosis
Pulmonary Artery
/ physiopathology
Pulmonary Embolism
/ complications
Retrospective Studies
Vascular Resistance
Ventricular Function, Right
Balloon pulmonary angioplasty
Cardiac index
Chronic thromboembolic pulmonary hypertension
Mixed venous oxygen saturation
Renal function
Journal
Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
09
01
2018
accepted:
26
10
2018
pubmed:
6
11
2018
medline:
18
5
2019
entrez:
3
11
2018
Statut:
ppublish
Résumé
Balloon pulmonary angioplasty (BPA) has emerged as an effective treatment for patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Renal function has been identified as a prognostic marker in patients with pulmonary hypertension in previous studies. We, therefore, aimed to investigate the clinical parameters associated with improvements in renal function in patients with CTEPH. A total of 45 consecutive patients with inoperable CTEPH undergoing BPA (mean age 62.2 ± 15.1 years) were included in the study. We evaluated the patients' clinical characteristics at baseline and at 1-year post-BPA, and investigated the association between renal function and hemodynamic parameters, including right heart function. Hemodynamics and renal function showed sustained improvements at 1 year after BPA in 64.4% of patients. Improved estimated glomerular filtration rate (eGFR) was significantly correlated with increased cardiac index (r = 0.433, p = 0.003) and mixed venous oxygen saturation (SvO
Identifiants
pubmed: 30386916
doi: 10.1007/s00380-018-1284-4
pii: 10.1007/s00380-018-1284-4
doi:
Substances chimiques
Oxygen
S88TT14065
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
688-697Références
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