Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes.

Adult Aged Blood Glucose / metabolism DNA Methylation / physiology Diabetes Mellitus, Type 2 / blood Female Humans Insulin-Like Growth Factor Binding Protein 2 / blood Male Middle Aged Phenotype Prospective Studies

Journal

Diabetes
ISSN: 1939-327X
Titre abrégé: Diabetes
Pays: United States
ID NLM: 0372763

Informations de publication

Date de publication:
01 2019
Historique:
received: 04 06 2018
accepted: 29 09 2018
pubmed: 7 11 2018
medline: 26 3 2019
entrez: 7 11 2018
Statut: ppublish

Résumé

Recent studies suggest that insulin-like growth factor binding protein 2 (IGFBP-2) may protect against type 2 diabetes, but population-based human studies are scarce. We aimed to investigate the prospective association of circulating IGFBP-2 concentrations and of differential methylation in the

Identifiants

DOI: 10.2337/db18-0620 PMID: 30396904
pubmed: 30396904
pii: db18-0620
doi: 10.2337/db18-0620
doi:

Substances chimiques

Blood Glucose 0
Insulin-Like Growth Factor Binding Protein 2 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

188-197

Informations de copyright

© 2018 by the American Diabetes Association.

Auteurs

Clemens Wittenbecher (C)

Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
ORCID: 0000-0001-7792-877X

Meriem Ouni (M)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.

Olga Kuxhaus (O)

Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, Germany.

Markus Jähnert (M)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.

Pascal Gottmann (P)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.

Andrea Teichmann (A)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.

Karina Meidtner (K)

Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.

Jennifer Kriebel (J)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München German Research Center for Environmental Health, Neuherberg, Germany.

Harald Grallert (H)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München German Research Center for Environmental Health, Neuherberg, Germany.

Tobias Pischon (T)

Molecular Epidemiology Research Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
Charité-Universitätsmedizin Berlin, Berlin, Germany.
Deutsches Zentrum für Herz-Kreislaufforschung e.V., partner site Berlin, Berlin, Germany.
Max Delbrück Center for Molecular Medicine and Berlin Institute of Health Biobank, Berlin, Germany.

Heiner Boeing (H)

Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.

Matthias B Schulze (MB)

Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.
German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Institute of Nutritional Sciences, University of Potsdam, Nuthetal, Germany.
ORCID: 0000-0002-0830-5277

Annette Schürmann (A)

German Center for Diabetes Research (DZD), München-Neuherberg, Germany schuermann@dife.de.
Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.
ORCID: 0000-0002-4113-4377

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Glycémie › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Phénomènes génétiques › Méthylation de l'ADN › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabète de type 2 › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Protéines de liaison aux IGF › Protéine-2 de liaison aux IGF › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Insulin-Like Growth Factor Binding Protein 2...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Insulin-Like Growth Factor Binding Protein 2...