Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury.
coronary angiography
high-sensitivity troponin
percutaneous coronary intervention
periprocedural myocardial injury
Journal
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
ISSN: 1804-7521
Titre abrégé: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
Pays: Czech Republic
ID NLM: 101140142
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
22
07
2018
accepted:
15
10
2018
pubmed:
7
11
2018
medline:
9
6
2020
entrez:
7
11
2018
Statut:
ppublish
Résumé
While there have been a number of studies reporting the incidence and implications of elevated troponin levels after percutaneous coronary intervention (PCI), the body of information about the incidence, associations, and implications of elevated troponin levels following coronary angiography (CAG) is limited. A total of 220 consecutive patients with stable coronary artery disease or intermediate or low-risk acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS) were included in our study. High-sensitivity cardiac troponin I (hs-cTnI) levels were measured before and after coronary angiography (CAG) in patients with or without PCI and correlated with a number of clinical variables. Hs-cTnI elevations above the 99 While an asymptomatic elevation of hs-cTnI is a common finding after PCI, it does occur, quite surprisingly, also after CAG. Despite contradictory views regarding the clinical relevance of asymptomatic post-procedural elevated hs-cTnI levels, it is generally believed that a mild elevation is not associated with an increased risk. Still, it may pose a diagnostic quandary following a successful interventional procedure and even more so after an uncomplicated CAG. Clinicaltrials.gov - NCT02960321.
Sections du résumé
BACKGROUND
BACKGROUND
While there have been a number of studies reporting the incidence and implications of elevated troponin levels after percutaneous coronary intervention (PCI), the body of information about the incidence, associations, and implications of elevated troponin levels following coronary angiography (CAG) is limited.
MATERIALS AND METHODS
METHODS
A total of 220 consecutive patients with stable coronary artery disease or intermediate or low-risk acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS) were included in our study. High-sensitivity cardiac troponin I (hs-cTnI) levels were measured before and after coronary angiography (CAG) in patients with or without PCI and correlated with a number of clinical variables.
RESULTS
RESULTS
Hs-cTnI elevations above the 99
CONCLUSION
CONCLUSIONS
While an asymptomatic elevation of hs-cTnI is a common finding after PCI, it does occur, quite surprisingly, also after CAG. Despite contradictory views regarding the clinical relevance of asymptomatic post-procedural elevated hs-cTnI levels, it is generally believed that a mild elevation is not associated with an increased risk. Still, it may pose a diagnostic quandary following a successful interventional procedure and even more so after an uncomplicated CAG.
TRIAL REGISTRATION
BACKGROUND
Clinicaltrials.gov - NCT02960321.
Substances chimiques
Biomarkers
0
Troponin
0
Banques de données
ClinicalTrials.gov
['NCT02960321']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM