Family Mismatched Allogeneic Stem Cell Transplantation for Myelofibrosis: Report from the Chronic Malignancies Working Party of European Society for Blood and Marrow Transplantation.


Journal

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
ISSN: 1523-6536
Titre abrégé: Biol Blood Marrow Transplant
Pays: United States
ID NLM: 9600628

Informations de publication

Date de publication:
03 2019
Historique:
received: 19 12 2017
accepted: 19 10 2018
pubmed: 9 11 2018
medline: 29 1 2020
entrez: 9 11 2018
Statut: ppublish

Résumé

This analysis included 56 myelofibrosis (MF) patients transplanted from family mismatched donor between 2009 and 2015 enrolled in the European Society for Blood and Marrow Transplantation database. The median age was 57years (range, 38 to 72); 75% had primary MF and 25% had secondary MF. JAK2 V617F was mutated in 61%. Donors were HLA mismatched at 2 or more loci. Stem cells were sourced from bone marrow in 66% and peripheral blood in 34%. The median CD34

Identifiants

pubmed: 30408564
pii: S1083-8791(18)30650-5
doi: 10.1016/j.bbmt.2018.10.017
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

522-528

Informations de copyright

Copyright © 2018 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

Auteurs

Kavita Raj (K)

Department of Haematological Medicine,Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom. Electronic address: kavitaraj28@gmail.com.

Diderik-Jan Eikema (DJ)

Department of Medical Statistics & Bioinformatics, EBMT Statistical Unit, Leiden, The Netherlands.

Donal P McLornan (DP)

Department of Haematological Medicine,Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.

Eduardo Olavarria (E)

Department of Haematological Medicine, Hammersmith Hospital, London, United Kingdom.

Henric-Jan Blok (HJ)

Department of Medical Statistics & Bioinformatics, EBMT Statistical Unit, Leiden, The Netherlands.

Stefania Bregante (S)

Department of Haematology, Ospedale San Martino, Genova, Italy.

Fabio Ciceri (F)

Department of Hematology and Hematopoietic Stem Cell Transplantation Instituto Di Ricovero e Cura a Carattere Scientificio San Raffaele Scientific Institute, Milano, Italy.

Jakob Passweg (J)

Department of Internal Medicine, University Hospital, Basel, Switzerland.

Per Ljungman (P)

Division of Hematology, Karolinska University Hospital, Stockholm, Sweden.

Nicolaas Schaap (N)

Department of Hematology, Radboud University, Medical Centre, Nijmegen, The Netherlands.

Kristina Carlson (K)

Internal Medicine/Hematology, University Hospital, Uppsala, Sweden.

Tsila Zuckerman (T)

Depatment of Hematology and Bone marrow Transplantation,Rambam Medical Center, Haifa, Israel.

Liesbeth C de Wreede (LC)

Department of Medical Statistics & Bioinformatics, EBMT Statistical Unit, Leiden, The Netherlands; Deutsche Knochenmarkspenderdatei Clinical Trials Unit, Dresden, Germany.

Liisa Volin (L)

Department of Medicine, Helsinki University Central Hospital Comprehensive Cancer Center, Helsinki, Finland.

Yener Koc (Y)

Department of Oncology, Stem cell transplant unit, Medical Park Hospitals, Antalya, Turkey.

Jose Luis Diez-Martin (JL)

Department of Hematology, Instituto de investigación sanitaria Gregorio Marañon, Universidad Complutense Medicina, Madrid, Spain.

Peter Brossart (P)

Departmetn of Immuno-oncolgy and Rheumatology, Universitat Bonn, Bonn, Germany.

Dominik Wolf (D)

Departmetn of Immuno-oncolgy and Rheumatology, Universitat Bonn, Bonn, Germany.

Didier Blaise (D)

Department of Onco-Hematology, Transplantation and cell therapy unit, Institut Paoli Calmettes, Marseille, France.

Paolo Di Bartolomeo (PD)

Department of Hematology, Transfusion Medicine and Biotechnology, Ospedale Civile, Pescara, Italy.

Antonin Vitek (A)

Institute of Hematology and Blood Transfusion, Prague, Czech Rep.

Marie Robin (M)

Department of Hematology and Bone marrow transplantation, Hopital St. Louis, Paris, France.

Ibrahim Yakoub-Agha (I)

Department of Hematology, Lille University hospital INSERM U995, Universite de Lille, France.

Yves Chalandon (Y)

Hôpitaux Universitaires de Genève, Hematology Division and Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Nicolaus Kroger (N)

Department of Stem Cell Transplantation, University Hospital Eppendorf, Hamburg, Germany.

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Classifications MeSH