Coeliac disease under a microscope: Histological diagnostic features and confounding factors.

Celiac Disease / diagnosis Diagnosis, Differential Duodenum / metabolism Glutens / toxicity Humans Intestinal Mucosa / metabolism
Gluten Gut microbiota Intraepithelial lymphocyte (IEL) Microscopic enteritis Non-coeliac gluten-sensitivity

Journal

Computers in biology and medicine
ISSN: 1879-0534
Titre abrégé: Comput Biol Med
Pays: United States
ID NLM: 1250250

Informations de publication

Date de publication:
01 2019
Historique:
received: 15 07 2018
revised: 16 10 2018
accepted: 17 10 2018
pubmed: 10 11 2018
medline: 20 2 2020
entrez: 10 11 2018
Statut: ppublish

Résumé

Coeliac disease (CD) and gluten-related disorders represent an important cornerstone of the daily practice of gastroenterologists, endoscopists and dedicated histopathologists. Despite the knowledge of clinical, serological and histological typical lesions, there are some conditions to consider for differential diagnosis. From the first description of histology of CD, several studies were conducted to define similar findings suggestive for microscopic enteritis. Considering the establishment of early precursor lesions, the imbalance of gut microbiota is another point still requiring a detailed definition. This review assesses the importance of a right overview in case of suspected gluten-related disorders and the several conditions mimicking a similar histology.

Identifiants

DOI: 10.1016/j.compbiomed.2018.10.020 PMID: 30409469
pubmed: 30409469
pii: S0010-4825(18)30319-6
doi: 10.1016/j.compbiomed.2018.10.020
pii:
doi:

Substances chimiques

Glutens 8002-80-0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

335-338

Informations de copyright

Copyright © 2018 Elsevier Ltd. All rights reserved.

Auteurs

Giulia Gibiino (G)

Internal Medicine and, Gastroenterology and Hepatic Diseases Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address: giulia.gibiino@gmail.com.

Loris Lopetuso (L)

Internal Medicine and, Gastroenterology and Hepatic Diseases Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy.

Riccardo Ricci (R)

Institute of Pathology, IRCCS Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy.

Antonio Gasbarrini (A)

Internal Medicine and, Gastroenterology and Hepatic Diseases Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy.

Giovanni Cammarota (G)

Internal Medicine and, Gastroenterology and Hepatic Diseases Unit, IRCCS Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy.

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Classifications MeSH

questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Syndromes de malabsorption › Maladie coeliaque › Coeliac disease under a microscope:...
questionsmedicales.fr › Diagnostic › Diagnostic différentiel › Coeliac disease under a microscope:...
questionsmedicales.fr › Système digestif › Tube digestif › Tube digestif supérieur › Duodénum › Coeliac disease under a microscope:...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines végétales › Protéines de stockage des graines › Prolamines › Glutens › Coeliac disease under a microscope:...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Coeliac disease under a microscope:...
questionsmedicales.fr › Tissus › Membranes › Muqueuse › Muqueuse intestinale › Coeliac disease under a microscope:...