Prevalence and causes of blindness and vision impairment: magnitude, temporal trends and projections in South and Central Asia.
blindness
cataract
epidemiology
glaucoma
global burden of disease study
macular degeneration
refractive error
vision impairment
vision loss
vision loss expert group
Journal
The British journal of ophthalmology
ISSN: 1468-2079
Titre abrégé: Br J Ophthalmol
Pays: England
ID NLM: 0421041
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
22
03
2018
revised:
05
07
2018
accepted:
23
09
2018
pubmed:
10
11
2018
medline:
7
3
2020
entrez:
10
11
2018
Statut:
ppublish
Résumé
To assess prevalence and causes of vision loss in Central and South Asia. A systematic review of medical literature assessed the prevalence of blindness (presenting visual acuity<3/60 in the better eye), moderate and severe vision impairment (MSVI; presenting visual acuity <6/18 but ≥3/60) and mild vision impairment (MVI; presenting visual acuity <6/12 and ≥6/18) in Central and South Asia for 1990, 2010, 2015 and 2020. In Central and South Asia combined, age-standardised prevalences of blindness, MSVI and MVI in 2015 were for men and women aged 50+years, 3.72% (80% uncertainty interval (UI): 1.39-6.75) and 4.00% (80% UI: 1.41-7.39), 16.33% (80% UI: 8.55-25.47) and 17.65% (80% UI: 9.00-27.62), 11.70% (80% UI: 4.70-20.32) and 12.25% (80% UI:4.86-21.30), respectively, with a significant decrease in the study period for both gender. In South Asia in 2015, 11.76 million individuals (32.65% of the global blindness figure) were blind and 61.19 million individuals (28.3% of the global total) had MSVI. From 1990 to 2015, cataract (accounting for 36.58% of all cases with blindness in 2015) was the most common cause of blindness, followed by undercorrected refractive error (36.43%), glaucoma (5.81%), age-related macular degeneration (2.44%), corneal diseases (2.43%), diabetic retinopathy (0.16%) and trachoma (0.04%). For MSVI in South Asia 2015, most common causes were undercorrected refractive error (accounting for 66.39% of all cases with MSVI), followed by cataract (23.62%), age-related macular degeneration (1.31%) and glaucoma (1.09%). One-third of the global blind resided in South Asia in 2015, although the age-standardised prevalence of blindness and MSVI decreased significantly between 1990 and 2015.
Sections du résumé
BACKGROUND
To assess prevalence and causes of vision loss in Central and South Asia.
METHODS
A systematic review of medical literature assessed the prevalence of blindness (presenting visual acuity<3/60 in the better eye), moderate and severe vision impairment (MSVI; presenting visual acuity <6/18 but ≥3/60) and mild vision impairment (MVI; presenting visual acuity <6/12 and ≥6/18) in Central and South Asia for 1990, 2010, 2015 and 2020.
RESULTS
In Central and South Asia combined, age-standardised prevalences of blindness, MSVI and MVI in 2015 were for men and women aged 50+years, 3.72% (80% uncertainty interval (UI): 1.39-6.75) and 4.00% (80% UI: 1.41-7.39), 16.33% (80% UI: 8.55-25.47) and 17.65% (80% UI: 9.00-27.62), 11.70% (80% UI: 4.70-20.32) and 12.25% (80% UI:4.86-21.30), respectively, with a significant decrease in the study period for both gender. In South Asia in 2015, 11.76 million individuals (32.65% of the global blindness figure) were blind and 61.19 million individuals (28.3% of the global total) had MSVI. From 1990 to 2015, cataract (accounting for 36.58% of all cases with blindness in 2015) was the most common cause of blindness, followed by undercorrected refractive error (36.43%), glaucoma (5.81%), age-related macular degeneration (2.44%), corneal diseases (2.43%), diabetic retinopathy (0.16%) and trachoma (0.04%). For MSVI in South Asia 2015, most common causes were undercorrected refractive error (accounting for 66.39% of all cases with MSVI), followed by cataract (23.62%), age-related macular degeneration (1.31%) and glaucoma (1.09%).
CONCLUSIONS
One-third of the global blind resided in South Asia in 2015, although the age-standardised prevalence of blindness and MSVI decreased significantly between 1990 and 2015.
Identifiants
pubmed: 30409914
pii: bjophthalmol-2018-312292
doi: 10.1136/bjophthalmol-2018-312292
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
871-877Investigateurs
Rupert Bourne
(R)
Peter Ackland
(P)
Aries Arditi
(A)
Yaniv Barkana
(Y)
Banu Bozkurt
(B)
Tasanee Braithwaite
(T)
Alain Bron
(A)
Donald Budenz
(D)
Feng Cai
(F)
Robert Casson
(R)
Usha Chakravarthy
(U)
Jaewan Choi
(J)
Maria Vittoria Cicinelli
(MV)
Nathan Congdon
(N)
Reza Dana
(R)
Rakhi Dandona
(R)
Lalit Dandona
(L)
Aditi Das
(A)
Iva Dekaris
(I)
Monte Del Monte
(M)
Jenny Deva
(J)
Mohamed Dirani
(M)
Laura Dreer
(L)
Leon Ellwein
(L)
Marcela Frazier
(M)
Kevin Frick
(K)
David Friedman
(D)
Joao Furtado
(J)
Hua Gao
(H)
Andrew Gazzard
(A)
Ronnie George
(R)
Stephen Gichuhi
(S)
Victor Gonzalez
(V)
Billy Hammond
(B)
Mary Elizabeth Hartnett
(ME)
Minguang He
(M)
James Hejtmancik
(J)
Flavio Hirai
(F)
John Huang
(J)
April Ingram
(A)
Jonathan Javitt
(J)
Jost Jonas
(J)
Charlotte Joslin
(C)
Jill Keeffe
(J)
John Kempen
(J)
Moncef Khairallah
(M)
Rohit Khanna
(R)
Judy Kim
(J)
George Lambrou
(G)
Van Charles Lansingh
(VC)
Paolo Lanzetta
(P)
Janet Leasher
(J)
Jennifer Lim
(J)
Hans Limburg
(H)
Kaweh Mansour
(K)
Anu Mathew
(A)
Alan Morse
(A)
Beatriz Munoz
(B)
David Musch
(D)
Kovin Naidoo
(K)
Vinay Nangia
(V)
Maria Palaicu
(M)
Maurizio Battaglia Parodi
(MB)
Fernando Yaacov Pena
(FY)
Konrad Pesudovs
(K)
Tunde Peto
(T)
Harry Quigley
(H)
Murugesan Raju
(M)
Pradeep Ramulu
(P)
Serge Resnikof
(S)
Dana Reza
(D)
Alan Robin
(A)
Luca Rossetti
(L)
Jinan Saaddine
(J)
Mya Sandar
(M)
Janet Serle
(J)
Tueng Shen
(T)
Rajesh Shetty
(R)
Pamela Sieving
(P)
Juan Carlos Silva
(JC)
Alex Silvester
(A)
Rita S Sitorus
(RS)
Dwight Stambolian
(D)
Gretchen Stevens
(G)
Hugh Taylor
(H)
Jaime Tejedor
(J)
James Tielsch
(J)
Fotis Topouzis
(F)
Miltiadis Tsilimbaris
(M)
Jan van Meurs
(J)
Rohit Varma
(R)
Gianni Virgili
(G)
Jimmy Volmink
(J)
Ya Xing Wang
(YX)
Ning-Li Wang
(NL)
Sheila West
(S)
Peter Wiedemann
(P)
Tien Wong
(T)
Richard Wormald
(R)
Yingfeng Zheng
(Y)
Informations de copyright
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: JBJ is the patent holder with Biocompatibles UK (Farnham, Surrey, UK) (Title: Treatment of eye diseases using encapsulated cells encoding and secreting neuroprotective factor and / or anti-angiogenic factor; Patent number: 20120263794) and Patent application with University of Heidelberg (Heidelberg, Germany) (Title: Agents for use in the therapeutic or prophylactic treatment of myopia or hyperopia; Europäische Patentanmeldung 15 000 771.4. SR is the consultant for Brien Holden Vision Institute.