Serological evidence of human infection by bat orthoreovirus in Singapore.
bat
luciferase immunoprecipitation system (LIPS)
orthoreovirus
spillover
virus neutralization test (VNT)
Journal
Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
11
09
2018
accepted:
31
10
2018
pubmed:
10
11
2018
medline:
18
3
2020
entrez:
10
11
2018
Statut:
ppublish
Résumé
To determine whether Pteropine orthoreovirus (PRV) exposure has occurred in Singapore, we tested 856 individuals from an existing serum panel collected from 2005-2013. After an initial screen with luciferase immunoprecipitation system and secondary confirmation with virus neutralization test, we identified at least seven individuals with specific antibodies against PRV in both assays. Our findings confirm that PRV spillover into human populations is relatively common in this region of the world.
Substances chimiques
Antibodies, Viral
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
707-710Informations de copyright
© 2018 Wiley Periodicals, Inc.