Use of gadolinium contrast agents in paediatric population: Donald Rumsfeld meets Hippocrates!


Journal

The British journal of radiology
ISSN: 1748-880X
Titre abrégé: Br J Radiol
Pays: England
ID NLM: 0373125

Informations de publication

Date de publication:
Feb 2019
Historique:
pubmed: 10 11 2018
medline: 9 2 2019
entrez: 10 11 2018
Statut: ppublish

Résumé

Gadolinium is a contrast agent that is used in MRI. There is new evidence that gadolinium accumulates in a patient's body and the effects of this accumulation is unknown. This has resulted in different advice being given by European Medicine Agency and U.S. Food and Drug Administration. The European Medicine Agency recommended stopping the use of linear Gadolinium agents (requiring more proof of safety) while the Food and Drug Administration continues to permit its use (requiring more proof of harm). Gadolinium should be used if deemed clinically necessary. Children and parents should be informed of the benefits and potential harm of using gadolinium-based contrast. It is up for debate whether those imaged before with gadolinium will benefit from being informed of new evidence.

Identifiants

pubmed: 30412428
doi: 10.1259/bjr.20180746
pmc: PMC6404820
doi:

Substances chimiques

Contrast Media 0
Gadolinium AU0V1LM3JT

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20180746

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Auteurs

Ruchir Shah (R)

1 UCL Medical School, UCL , London , UK.

Felice D'Arco (F)

2 Great Ormond Street Hospital , London , UK.

Bruno Soares (B)

3 John Hopkins Hospital , Baltimore, MD , USA.

Jessica Cooper (J)

2 Great Ormond Street Hospital , London , UK.

Joe Brierley (J)

2 Great Ormond Street Hospital , London , UK.

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Classifications MeSH